NDUB1_PANTR
ID NDUB1_PANTR Reviewed; 58 AA.
AC Q0MQC6;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1;
DE AltName: Full=Complex I-MNLL;
DE Short=CI-MNLL;
DE AltName: Full=NADH-ubiquinone oxidoreductase MNLL subunit;
GN Name=NDUFB1;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA Wallace D.C.;
RT "Adaptive selection of mitochondrial complex I subunits during primate
RT radiation.";
RL Gene 378:11-18(2006).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I) that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000250|UniProtKB:O75438}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000250|UniProtKB:O75438}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:O75438}; Single-pass membrane protein
CC {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:O75438}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB1 subunit family.
CC {ECO:0000305}.
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DR EMBL; DQ885708; ABH12217.1; -; mRNA.
DR AlphaFoldDB; Q0MQC6; -.
DR SMR; Q0MQC6; -.
DR STRING; 9598.ENSPTRP00000011334; -.
DR PaxDb; Q0MQC6; -.
DR eggNOG; ENOG502S6X0; Eukaryota.
DR InParanoid; Q0MQC6; -.
DR Proteomes; UP000002277; Unplaced.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR InterPro; IPR012575; NDUB1.
DR PANTHER; PTHR15222; PTHR15222; 1.
DR Pfam; PF08040; NADH_oxidored; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..58
FT /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT subunit 1"
FT /id="PRO_0000251824"
FT TRANSMEM 11..27
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 58 AA; 6961 MW; 2281D89AAE61EA52 CRC64;
MVNLLQIVRD HWVHVLVPMG FVIGCYLDRK SDERLTAFRN KSMLFKRELQ PSEEVTWK