NDUB1_PONAB
ID NDUB1_PONAB Reviewed; 58 AA.
AC P0CB73; Q0MQC4; Q5R683;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1;
DE AltName: Full=Complex I-MNLL;
DE Short=CI-MNLL;
DE AltName: Full=NADH-ubiquinone oxidoreductase MNLL subunit;
GN Name=NDUFB1;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I) that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000250|UniProtKB:O75438}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000250|UniProtKB:O75438}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:O75438}; Single-pass membrane protein
CC {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:O75438}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB1 subunit family.
CC {ECO:0000305}.
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DR EMBL; CR860612; CAH92733.1; -; mRNA.
DR RefSeq; NP_001126594.1; NM_001133122.1.
DR AlphaFoldDB; P0CB73; -.
DR SMR; P0CB73; -.
DR STRING; 9601.ENSPPYP00000006908; -.
DR GeneID; 100173590; -.
DR KEGG; pon:100173590; -.
DR CTD; 4707; -.
DR eggNOG; ENOG502S6X0; Eukaryota.
DR InParanoid; P0CB73; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR InterPro; IPR012575; NDUB1.
DR PANTHER; PTHR15222; PTHR15222; 1.
DR Pfam; PF08040; NADH_oxidored; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..58
FT /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT subunit 1"
FT /id="PRO_0000118828"
FT TRANSMEM 11..27
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 58 AA; 6860 MW; 21B1E910AE796A2B CRC64;
MVNLLQIVRD HWVHVLVPMG FVIGCYLDKK SDEQLTAFRN KSMLFKRGLQ PNEEVTWK