NDUB2_CAEEL
ID NDUB2_CAEEL Reviewed; 160 AA.
AC Q20412;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Probable NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial;
DE Flags: Precursor;
GN ORFNames=F44G4.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Bristol N2;
RA Kohara Y., Shin-i T., Suzuki Y., Sugano S., Potdevin M., Thierry-Mieg Y.,
RA Thierry-Mieg D., Thierry-Mieg J.;
RT "The Caenorhabditis elegans transcriptome project, a complementary view of
RT the genome.";
RL Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB2 subunit family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z49910; CAA90118.1; -; Genomic_DNA.
DR EMBL; AF304128; AAG50241.1; -; mRNA.
DR PIR; T22205; T22205.
DR RefSeq; NP_495919.1; NM_063518.7.
DR AlphaFoldDB; Q20412; -.
DR STRING; 6239.F44G4.2; -.
DR EPD; Q20412; -.
DR PaxDb; Q20412; -.
DR PeptideAtlas; Q20412; -.
DR EnsemblMetazoa; F44G4.2.1; F44G4.2.1; WBGene00009712.
DR GeneID; 174435; -.
DR KEGG; cel:CELE_F44G4.2; -.
DR UCSC; F44G4.2.1; c. elegans.
DR CTD; 174435; -.
DR WormBase; F44G4.2; CE02229; WBGene00009712; -.
DR eggNOG; ENOG502SBCC; Eukaryota.
DR GeneTree; ENSGT00390000004044; -.
DR HOGENOM; CLU_1629042_0_0_1; -.
DR InParanoid; Q20412; -.
DR OMA; PEYWGDH; -.
DR OrthoDB; 1310625at2759; -.
DR Reactome; R-CEL-6799198; Complex I biogenesis.
DR PRO; PR:Q20412; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00009712; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:WormBase.
DR GO; GO:0005739; C:mitochondrion; HDA:WormBase.
DR InterPro; IPR026627; NDUFB2_animal.
DR PANTHER; PTHR15223; PTHR15223; 1.
DR Pfam; PF14813; NADH_B2; 1.
PE 2: Evidence at transcript level;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transit peptide; Transport.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT CHAIN ?..160
FT /note="Probable NADH dehydrogenase [ubiquinone] 1 beta
FT subcomplex subunit 2, mitochondrial"
FT /id="PRO_0000020044"
SQ SEQUENCE 160 AA; 18486 MW; 6E1F299D71273AC4 CRC64;
MLGNKFVAQL ALQHLRNRGL VNSPSRLTFV RNRFAWGSDA VGPNVPVGGK MGASENPELH
TYDGDYRGTI SKGDKPIPDY FYRTPTTGRT YIDRCVTYFI SAVIWAWFSY HMYYHSGHLL
GHWYMPYLSE FTDEELGIPK DSAEDPEYWG NHKKEYGTYR
