NDUB2_PANTR
ID NDUB2_PANTR Reviewed; 105 AA.
AC Q0MQC9;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial;
DE AltName: Full=Complex I-AGGG;
DE Short=CI-AGGG;
DE AltName: Full=NADH-ubiquinone oxidoreductase AGGG subunit;
DE Flags: Precursor;
GN Name=NDUFB2;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA Wallace D.C.;
RT "Adaptive selection of mitochondrial complex I subunits during primate
RT radiation.";
RL Gene 378:11-18(2006).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000250|UniProtKB:O95178}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000250|UniProtKB:O95178}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:O95178}; Peripheral membrane protein
CC {ECO:0000250|UniProtKB:O95178}; Matrix side
CC {ECO:0000250|UniProtKB:O95178}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB2 subunit family.
CC {ECO:0000305}.
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DR EMBL; DQ885705; ABH12214.1; -; mRNA.
DR RefSeq; NP_001065266.1; NM_001071798.1.
DR RefSeq; XP_009452505.1; XM_009454230.2.
DR AlphaFoldDB; Q0MQC9; -.
DR SMR; Q0MQC9; -.
DR STRING; 9598.ENSPTRP00000033870; -.
DR PaxDb; Q0MQC9; -.
DR Ensembl; ENSPTRT00000036630; ENSPTRP00000033870; ENSPTRG00000019771.
DR GeneID; 463780; -.
DR KEGG; ptr:463780; -.
DR CTD; 4708; -.
DR VGNC; VGNC:4441; NDUFB2.
DR eggNOG; ENOG502S524; Eukaryota.
DR GeneTree; ENSGT00390000004044; -.
DR HOGENOM; CLU_177133_1_0_1; -.
DR InParanoid; Q0MQC9; -.
DR OMA; SALMWFW; -.
DR TreeFam; TF316619; -.
DR Proteomes; UP000002277; Chromosome 7.
DR Bgee; ENSPTRG00000019771; Expressed in skeletal muscle tissue and 21 other tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR InterPro; IPR026627; NDUFB2_animal.
DR PANTHER; PTHR15223; PTHR15223; 1.
DR Pfam; PF14813; NADH_B2; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transit peptide; Transport.
FT TRANSIT 1..33
FT /note="Mitochondrion"
FT /evidence="ECO:0000250"
FT CHAIN 34..105
FT /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT subunit 2, mitochondrial"
FT /id="PRO_0000251826"
FT REGION 85..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 105 AA; 12156 MW; 038D67DF6890AA1F CRC64;
MSDLTRLASF ARVGGRLFRS GRARTAGDGG VRHAGGGVHI EPRYRQFPQL TRSQVFQSEF
FSGLMWFWIL WRFWHDSEEV LGHFPYPDPS QWTDEELGIP PDDED
