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NDUB4_GORGO
ID   NDUB4_GORGO             Reviewed;         129 AA.
AC   Q0MQD4;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4;
DE   AltName: Full=Complex I-B15;
DE            Short=CI-B15;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B15 subunit;
GN   Name=NDUFB4;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O95168}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:O95168}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O95168}; Single-pass membrane protein
CC       {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:O95168}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFB4 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; DQ885700; ABH12209.1; -; mRNA.
DR   RefSeq; NP_001266482.1; NM_001279553.1.
DR   AlphaFoldDB; Q0MQD4; -.
DR   SMR; Q0MQD4; -.
DR   STRING; 9593.ENSGGOP00000013576; -.
DR   Ensembl; ENSGGOT00000013967; ENSGGOP00000013576; ENSGGOG00000013923.
DR   GeneID; 101129506; -.
DR   KEGG; ggo:101129506; -.
DR   CTD; 4710; -.
DR   eggNOG; ENOG502S2HF; Eukaryota.
DR   GeneTree; ENSGT00390000007133; -.
DR   HOGENOM; CLU_123402_0_0_1; -.
DR   InParanoid; Q0MQD4; -.
DR   OMA; PLFFWFY; -.
DR   OrthoDB; 1434967at2759; -.
DR   Proteomes; UP000001519; Chromosome 3.
DR   Bgee; ENSGGOG00000013923; Expressed in heart and 6 other tissues.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   InterPro; IPR009866; NADH_UbQ_OxRdtase_NDUFB4_su.
DR   PANTHER; PTHR15469; PTHR15469; 1.
DR   Pfam; PF07225; NDUF_B4; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Phosphoprotein; Reference proteome;
KW   Respiratory chain; Transmembrane; Transmembrane helix; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:P48305"
FT   CHAIN           2..129
FT                   /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT                   subunit 4"
FT                   /id="PRO_0000251831"
FT   TRANSMEM        88..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:P48305"
FT   MOD_RES         26
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:O95168"
SQ   SEQUENCE   129 AA;  15209 MW;  E5060D0BF46FFF28 CRC64;
     MSFPKYKPSS LRTLPETLDP AEYNISPETR RAQAERLAIR AQLKREYLLQ YNDPNRRGLI
     ENPALLRWAY ARTINVYPNF RPTPKNSLMG ALCGFGPLIF IYYIIKTERD RKEKLIQEGK
     LDRTFHLSY
 
 
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