ID   NDUB5_GORGO             Reviewed;         189 AA.
AC   Q0MQD7;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial;
DE   AltName: Full=Complex I-SGDH;
DE            Short=CI-SGDH;
DE   AltName: Full=NADH-ubiquinone oxidoreductase SGDH subunit;
DE   Flags: Precursor;
GN   Name=NDUFB5;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O43674}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:O43674}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O43674}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:O43674}; Matrix side
CC       {ECO:0000250|UniProtKB:O43674}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFB5 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; DQ885697; ABH12206.1; -; mRNA.
DR   RefSeq; NP_001266523.1; NM_001279594.1.
DR   AlphaFoldDB; Q0MQD7; -.
DR   SMR; Q0MQD7; -.
DR   STRING; 9593.ENSGGOP00000005115; -.
DR   Ensembl; ENSGGOT00000049540; ENSGGOP00000045593; ENSGGOG00000005222.
DR   GeneID; 101148993; -.
DR   KEGG; ggo:101148993; -.
DR   CTD; 4711; -.
DR   eggNOG; KOG4632; Eukaryota.
DR   GeneTree; ENSGT00390000009980; -.
DR   InParanoid; Q0MQD7; -.
DR   OrthoDB; 1251699at2759; -.
DR   Proteomes; UP000001519; Chromosome 3.
DR   Bgee; ENSGGOG00000005222; Expressed in heart and 6 other tissues.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   InterPro; IPR019173; NADH_UbQ_OxRdtase_B5_su.
DR   PANTHER; PTHR13178; PTHR13178; 1.
DR   Pfam; PF09781; NDUF_B5; 1.
PE   2: Evidence at transcript level;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Respiratory chain; Transit peptide; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..46
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           47..189
FT                   /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT                   subunit 5, mitochondrial"
FT                   /id="PRO_0000251833"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   189 AA;  21750 MW;  66D288F7AB7FD5C5 CRC64;
     MAAMSLLRRV SVTAVAALSG RPLGTRLGFG GFLTRGFPKA AAPVRHSGDH GKRLFVIRPS
     RFYDRRFLKL LRFYIALTGI PVAIFITLVN VFIGQAELAE IPEGYVPEHW EYYKHPISRW
     IARNFYDSPE KIYERTMAVL QIEAEKAELR VKELEVRKLM HVRGDGPWYY YETIDKELID
     HSPKATPDN