位置:首页 > 蛋白库 > NDUB6_PANTR
NDUB6_PANTR
ID   NDUB6_PANTR             Reviewed;         128 AA.
AC   Q0MQE1;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;
DE   AltName: Full=Complex I-B17;
DE            Short=CI-B17;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B17 subunit;
GN   Name=NDUFB6;
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O95139}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:O95139}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O95139}; Single-pass membrane protein
CC       {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:O95139}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFB6 subunit family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ885693; ABH12202.1; -; mRNA.
DR   RefSeq; NP_001233137.1; NM_001246208.1.
DR   AlphaFoldDB; Q0MQE1; -.
DR   SMR; Q0MQE1; -.
DR   STRING; 9598.ENSPTRP00000035649; -.
DR   PaxDb; Q0MQE1; -.
DR   Ensembl; ENSPTRT00000080811; ENSPTRP00000091097; ENSPTRG00000020846.
DR   GeneID; 100611615; -.
DR   KEGG; ptr:100611615; -.
DR   CTD; 4712; -.
DR   VGNC; VGNC:4800; NDUFB6.
DR   eggNOG; KOG4633; Eukaryota.
DR   GeneTree; ENSGT00390000007535; -.
DR   HOGENOM; CLU_171928_0_0_1; -.
DR   InParanoid; Q0MQE1; -.
DR   OMA; KYHVNTK; -.
DR   OrthoDB; 1545413at2759; -.
DR   TreeFam; TF328587; -.
DR   Proteomes; UP000002277; Chromosome 9.
DR   Bgee; ENSPTRG00000020846; Expressed in heart and 21 other tissues.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IBA:GO_Central.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   InterPro; IPR019174; NADH_DH_b-subcmplx_su6.
DR   PANTHER; PTHR15083; PTHR15083; 1.
DR   Pfam; PF09782; NDUF_B6; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW   Transmembrane; Transmembrane helix; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:O95139"
FT   CHAIN           2..128
FT                   /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT                   subunit 6"
FT                   /id="PRO_0000251837"
FT   TRANSMEM        68..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylthreonine"
FT                   /evidence="ECO:0000250|UniProtKB:O95139"
FT   MOD_RES         24
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UIU2"
SQ   SEQUENCE   128 AA;  15489 MW;  E8F419F5EB154D0B CRC64;
     MTGYTPDEKL RLQQLRELRR RWLKDQELSP REPVLPPQKM GPMEKFWNKF LENKSPWRKM
     VHGVYKKSIF VFTHVLVPVW IIHYYMKYHV SEKPYGIVEK KSRIFPGDTI LETGEVIPPM
     KEFPDQHH
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024