ID   NDUB6_PONPY             Reviewed;         128 AA.
AC   P0CB94; Q0MQD9; Q5RBV5;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;
DE   AltName: Full=Complex I-B17;
DE            Short=CI-B17;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B17 subunit;
GN   Name=NDUFB6;
OS   Pongo pygmaeus (Bornean orangutan).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O95139}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:O95139}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O95139}; Single-pass membrane protein
CC       {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:O95139}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFB6 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; DQ885695; ABH12204.1; -; mRNA.
DR   AlphaFoldDB; P0CB94; -.
DR   SMR; P0CB94; -.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   InterPro; IPR019174; NADH_DH_b-subcmplx_su6.
DR   PANTHER; PTHR15083; PTHR15083; 1.
DR   Pfam; PF09782; NDUF_B6; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Respiratory chain; Transmembrane;
KW   Transmembrane helix; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:O95139"
FT   CHAIN           2..128
FT                   /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT                   subunit 6"
FT                   /id="PRO_0000389265"
FT   TRANSMEM        68..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         2
FT                   /note="N-acetylthreonine"
FT                   /evidence="ECO:0000250|UniProtKB:O95139"
FT   MOD_RES         24
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UIU2"
SQ   SEQUENCE   128 AA;  15489 MW;  E8E1EC15EB155711 CRC64;
     MTGYTPDEKL RLQQLRELRR RWLKDQELSP REPVLPPQKM GPMEKFWNKF LENKSPWRKM
     VHGVYQKSIF VFTHVLVPVW IIHYYMKYHV SEKPYGIVEK KSRIFPGDTI LETGEVIPPM
     KEFPDQHH