ID   NDUB7_DICDI             Reviewed;         112 AA.
AC   Q54V61;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7;
GN   Name=ndufb7; ORFNames=DDB_G0280595;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P17568}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:P17568}. Mitochondrion intermembrane space
CC       {ECO:0000250|UniProtKB:P17568}.
CC   -!- DOMAIN: Contains two C-X9-C motifs that are predicted to form a helix-
CC       coil-helix structure, permitting the formation of intramolecular
CC       disulfide bonds. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFB7 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000037; EAL67099.1; -; Genomic_DNA.
DR   RefSeq; XP_641070.1; XM_635978.1.
DR   AlphaFoldDB; Q54V61; -.
DR   SMR; Q54V61; -.
DR   STRING; 44689.DDB0206064; -.
DR   PaxDb; Q54V61; -.
DR   EnsemblProtists; EAL67099; EAL67099; DDB_G0280595.
DR   GeneID; 8622628; -.
DR   KEGG; ddi:DDB_G0280595; -.
DR   dictyBase; DDB_G0280595; ndufb7.
DR   eggNOG; KOG3468; Eukaryota.
DR   HOGENOM; CLU_2150613_0_0_1; -.
DR   InParanoid; Q54V61; -.
DR   OMA; CQYDEYL; -.
DR   PhylomeDB; Q54V61; -.
DR   PRO; PR:Q54V61; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; IBA:GO_Central.
DR   InterPro; IPR008698; NDUB7.
DR   PANTHER; PTHR20900; PTHR20900; 1.
DR   Pfam; PF05676; NDUF_B7; 1.
DR   PROSITE; PS51808; CHCH; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW   Transport.
FT   CHAIN           1..112
FT                   /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT                   subunit 7"
FT                   /id="PRO_0000330323"
FT   DOMAIN          35..77
FT                   /note="CHCH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           38..48
FT                   /note="Cx9C motif 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           59..69
FT                   /note="Cx9C motif 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        38..69
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        48..59
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ   SEQUENCE   112 AA;  13271 MW;  7A9865797941D43A CRC64;
     MTGHAPESTF NADGSRKMIA TQQQCEDKNL PLSFRDYCAH LLIPLNDCRV STYYAPWKCM
     DEKHAYEGCQ YDEYLYRKIK KSEQDEAERI KREVVIEKEN PKDRPYEEIK LS