NDUB8_ARATH
ID NDUB8_ARATH Reviewed; 125 AA.
AC Q9FGK0;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial;
DE Flags: Precursor;
GN OrderedLocusNames=At5g47570; ORFNames=MNJ7.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Complex I is composed of at least 49 different subunits.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Single-pass membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB8 subunit family.
CC {ECO:0000305}.
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DR EMBL; AB025628; BAB09083.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95533.1; -; Genomic_DNA.
DR EMBL; AF462836; AAL58924.1; -; mRNA.
DR EMBL; AY097354; AAM19870.1; -; mRNA.
DR EMBL; AY084983; AAM61542.1; -; mRNA.
DR RefSeq; NP_568684.1; NM_124130.5.
DR PDB; 7AQW; EM; 3.17 A; l=1-125.
DR PDB; 7AR7; EM; 3.72 A; l=76-121.
DR PDB; 7AR8; EM; 3.53 A; l=1-125.
DR PDB; 7ARB; EM; 3.41 A; l=1-125.
DR PDBsum; 7AQW; -.
DR PDBsum; 7AR7; -.
DR PDBsum; 7AR8; -.
DR PDBsum; 7ARB; -.
DR AlphaFoldDB; Q9FGK0; -.
DR SMR; Q9FGK0; -.
DR BioGRID; 20055; 5.
DR IntAct; Q9FGK0; 7.
DR STRING; 3702.AT5G47570.1; -.
DR iPTMnet; Q9FGK0; -.
DR PaxDb; Q9FGK0; -.
DR PRIDE; Q9FGK0; -.
DR ProteomicsDB; 236820; -.
DR EnsemblPlants; AT5G47570.1; AT5G47570.1; AT5G47570.
DR GeneID; 834807; -.
DR Gramene; AT5G47570.1; AT5G47570.1; AT5G47570.
DR KEGG; ath:AT5G47570; -.
DR Araport; AT5G47570; -.
DR TAIR; locus:2169003; AT5G47570.
DR eggNOG; ENOG502RZB4; Eukaryota.
DR HOGENOM; CLU_151534_0_0_1; -.
DR InParanoid; Q9FGK0; -.
DR OMA; NRPLHVN; -.
DR OrthoDB; 1466518at2759; -.
DR PhylomeDB; Q9FGK0; -.
DR PRO; PR:Q9FGK0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGK0; baseline and differential.
DR Genevisible; Q9FGK0; AT.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IDA:TAIR.
DR InterPro; IPR038863; Put_Complex_I_su8.
DR PANTHER; PTHR36401; PTHR36401; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Electron transport; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW Transit peptide; Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..29
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 30..125
FT /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT subunit 8, mitochondrial"
FT /id="PRO_0000410998"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TURN 49..52
FT /evidence="ECO:0007829|PDB:7AQW"
FT HELIX 75..99
FT /evidence="ECO:0007829|PDB:7AQW"
FT HELIX 101..104
FT /evidence="ECO:0007829|PDB:7AQW"
FT HELIX 113..117
FT /evidence="ECO:0007829|PDB:7AQW"
FT HELIX 119..121
FT /evidence="ECO:0007829|PDB:7AQW"
SQ SEQUENCE 125 AA; 13211 MW; 151F9B8D76AB26D9 CRC64;
MAGRLSGVAS RIMGGNGVVA RSVGSSLRQR AGMGLPVGKH IVPDKPLSVN DELMWDNGTA
FPEPCIDRIA DTVGKYEALA WLSGGLGFFV GLGLLAVLND KASKVPFTPR VYPYDNLRVE
LGGEP
