NDUBA_PANTR
ID NDUBA_PANTR Reviewed; 172 AA.
AC Q0MQF3;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10;
DE AltName: Full=Complex I-PDSW;
DE Short=CI-PDSW;
DE AltName: Full=NADH-ubiquinone oxidoreductase PDSW subunit;
GN Name=NDUFB10;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA Wallace D.C.;
RT "Adaptive selection of mitochondrial complex I subunits during primate
RT radiation.";
RL Gene 378:11-18(2006).
CC -!- FUNCTION: Accessory subunit that is involved in the functional assembly
CC of the mitochondrial respiratory chain complex I. Complex I has an NADH
CC dehydrogenase activity with ubiquinone as an immediate electron
CC acceptor and mediates the transfer of electrons from NADH to the
CC respiratory chain. {ECO:0000250|UniProtKB:O96000}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits. Interacts with
CC CHCHD4. {ECO:0000250|UniProtKB:O96000}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:O96000}; Peripheral membrane protein
CC {ECO:0000250|UniProtKB:O96000}; Matrix side
CC {ECO:0000250|UniProtKB:O96000}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB10 subunit family.
CC {ECO:0000305}.
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DR EMBL; DQ885681; ABH12190.1; -; mRNA.
DR RefSeq; NP_001065292.1; NM_001071824.1.
DR AlphaFoldDB; Q0MQF3; -.
DR SMR; Q0MQF3; -.
DR STRING; 9598.ENSPTRP00000013017; -.
DR PaxDb; Q0MQF3; -.
DR Ensembl; ENSPTRT00000014050; ENSPTRP00000013017; ENSPTRG00000007618.
DR GeneID; 746648; -.
DR KEGG; ptr:746648; -.
DR CTD; 4716; -.
DR VGNC; VGNC:5849; NDUFB10.
DR eggNOG; KOG4009; Eukaryota.
DR GeneTree; ENSGT00390000006348; -.
DR HOGENOM; CLU_112615_1_0_1; -.
DR InParanoid; Q0MQF3; -.
DR OMA; ERMKACQ; -.
DR OrthoDB; 1364322at2759; -.
DR TreeFam; TF105792; -.
DR Proteomes; UP000002277; Chromosome 16.
DR Bgee; ENSPTRG00000007618; Expressed in heart and 20 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR InterPro; IPR019377; NADH_UbQ_OxRdtase_su10.
DR InterPro; IPR039993; NDUFB10.
DR PANTHER; PTHR13094; PTHR13094; 1.
DR Pfam; PF10249; NDUFB10; 1.
PE 2: Evidence at transcript level;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Phosphoprotein; Reference proteome; Respiratory chain; Transport.
FT CHAIN 1..172
FT /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT subunit 10"
FT /id="PRO_0000251844"
FT MOD_RES 145
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:O96000"
SQ SEQUENCE 172 AA; 20821 MW; 25B34E80C3332DA5 CRC64;
MPDSWDKDVY PEPPRRTPVQ PNLIVYMMKA FDLIVDRPVT LVREFIERQH AKNRYYYYHR
QYRRVPDITE CKEEDIMCMY EAEMQWRRDY KVDQEIINIM QDRLKACQQR EGQNYQQNCI
KEVEQFTQVA KAYQDRYQDL GAYSSARKCL AKQRQRMLQE RKAAKEAAAA TS
