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NDUBB_CRIGR
ID   NDUBB_CRIGR             Reviewed;         151 AA.
AC   Q6DQX6;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial;
DE   AltName: Full=Complex I-ESSS;
DE            Short=CI-ESSS;
DE   AltName: Full=NADH-ubiquinone oxidoreductase ESSS subunit;
DE   Flags: Precursor;
GN   Name=NDUFB11;
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15265046; DOI=10.1111/j.1432-1033.2004.04260.x;
RA   Potluri P., Yadava N., Scheffler I.E.;
RT   "The role of the ESSS protein in the assembly of a functional and stable
RT   mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase).";
RL   Eur. J. Biochem. 271:3265-3273(2004).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:Q9NX14}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits. Interacts with
CC       BCAP31. {ECO:0000250|UniProtKB:Q9NX14}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q9NX14}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q9NX14}. Note=The interaction with BCAP31
CC       mediates mitochondria localization. {ECO:0000250|UniProtKB:Q9NX14}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFB11 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; AY649405; AAT69237.1; -; mRNA.
DR   RefSeq; NP_001233718.1; NM_001246789.1.
DR   AlphaFoldDB; Q6DQX6; -.
DR   SMR; Q6DQX6; -.
DR   STRING; 10029.NP_001233718.1; -.
DR   Ensembl; ENSCGRT00001009851; ENSCGRP00001006288; ENSCGRG00001008464.
DR   GeneID; 100689361; -.
DR   KEGG; cge:100689361; -.
DR   CTD; 54539; -.
DR   eggNOG; KOG4808; Eukaryota.
DR   GeneTree; ENSGT00390000003022; -.
DR   OMA; CAQSHFR; -.
DR   OrthoDB; 1609364at2759; -.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   InterPro; IPR019329; NADH_UbQ_OxRdtase_ESSS_su.
DR   PANTHER; PTHR13327; PTHR13327; 1.
DR   Pfam; PF10183; ESSS; 1.
PE   2: Evidence at transcript level;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Respiratory chain; Transit peptide; Transmembrane; Transmembrane helix;
KW   Transport.
FT   TRANSIT         1..29
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           30..151
FT                   /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT                   subunit 11, mitochondrial"
FT                   /id="PRO_0000234303"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          39..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   151 AA;  17485 MW;  63781C815551BB1E CRC64;
     MAARLLSLCA RRLSVTAAVR GLPAAGVRWE SSRAVISPST VERKRQRQPT MHWQEDPESE
     DENVYAKNPD FHGYDQDPVV DVWNMRVVFF FGFSIVLVLG TTFMAYLPDY RMQEWARREA
     ERLVKYREAN GLPIMESNCF DPSKIQLPED E
 
 
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