NDUBB_PANTR
ID NDUBB_PANTR Reviewed; 153 AA.
AC Q0MQJ5;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial;
DE AltName: Full=Complex I-ESSS;
DE Short=CI-ESSS;
DE AltName: Full=NADH-ubiquinone oxidoreductase ESSS subunit;
DE Flags: Precursor;
GN Name=NDUFB11;
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA Wallace D.C.;
RT "Adaptive selection of mitochondrial complex I subunits during primate
RT radiation.";
RL Gene 378:11-18(2006).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000250|UniProtKB:Q9NX14}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits. Interacts with
CC BCAP31. {ECO:0000250|UniProtKB:Q9NX14}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:Q9NX14}; Single-pass membrane protein
CC {ECO:0000250|UniProtKB:Q9NX14}. Note=The interaction with BCAP31
CC mediates mitochondria localization. {ECO:0000250|UniProtKB:Q9NX14}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB11 subunit family.
CC {ECO:0000305}.
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DR EMBL; DQ885639; ABH12148.1; -; mRNA.
DR RefSeq; NP_001065278.1; NM_001071810.1.
DR RefSeq; XP_016798227.1; XM_016942738.1.
DR AlphaFoldDB; Q0MQJ5; -.
DR SMR; Q0MQJ5; -.
DR STRING; 9598.ENSPTRP00000037483; -.
DR PaxDb; Q0MQJ5; -.
DR GeneID; 473588; -.
DR KEGG; ptr:473588; -.
DR CTD; 54539; -.
DR eggNOG; KOG4808; Eukaryota.
DR HOGENOM; CLU_109862_0_0_1; -.
DR InParanoid; Q0MQJ5; -.
DR TreeFam; TF314671; -.
DR Proteomes; UP000002277; Unplaced.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR InterPro; IPR019329; NADH_UbQ_OxRdtase_ESSS_su.
DR PANTHER; PTHR13327; PTHR13327; 1.
DR Pfam; PF10183; ESSS; 1.
PE 2: Evidence at transcript level;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transit peptide; Transmembrane;
KW Transmembrane helix; Transport.
FT TRANSIT 1..29
FT /note="Mitochondrion"
FT /evidence="ECO:0000250"
FT CHAIN 30..153
FT /note="NADH dehydrogenase [ubiquinone] 1 beta subcomplex
FT subunit 11, mitochondrial"
FT /id="PRO_0000251846"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 40..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 153 AA; 17305 MW; 5908E8C455B796E2 CRC64;
MAAGLFGLSA RLLLAAAATR GLPAARVRWE SSFSRTVVAP SAVAGKRPPE PTTQWQEDPE
PEDENLYEKN PDSHGYDKDP VLDVWNMRLV FFFGVSIILV LGSTFVAYLP DYRMKEWSRR
EAERLVKYRE ANGLPIMESN CFDPSKIQLP EDE
