ID   NDUC1_PONAB             Reviewed;          77 AA.
AC   P0CB69; Q0MQF4; Q5R7L5; Q5R8I1;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial;
DE   AltName: Full=Complex I-KFYI;
DE            Short=CI-KFYI;
DE   AltName: Full=NADH-ubiquinone oxidoreductase KFYI subunit;
DE   Flags: Precursor;
GN   Name=NDUFC1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O43677}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC       {ECO:0000250|UniProtKB:O43677}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:Q02376}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q02376}; Matrix side
CC       {ECO:0000250|UniProtKB:Q02376}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFC1 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; CR859771; CAH91929.1; -; mRNA.
DR   EMBL; CR860100; CAH92245.1; -; mRNA.
DR   RefSeq; NP_001127482.1; NM_001134010.1.
DR   AlphaFoldDB; P0CB69; -.
DR   SMR; P0CB69; -.
DR   STRING; 9601.ENSPPYP00000016836; -.
DR   GeneID; 100174556; -.
DR   KEGG; pon:100174556; -.
DR   CTD; 4717; -.
DR   eggNOG; ENOG502SFTF; Eukaryota.
DR   InParanoid; P0CB69; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   InterPro; IPR026192; NDUFC1.
DR   PANTHER; PTHR17097; PTHR17097; 1.
DR   Pfam; PF15088; NADH_dh_m_C1; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Respiratory chain; Transit peptide; Transmembrane;
KW   Transmembrane helix; Transport.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           29..77
FT                   /note="NADH dehydrogenase [ubiquinone] 1 subunit C1,
FT                   mitochondrial"
FT                   /id="PRO_0000250209"
FT   TRANSMEM        42..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        18
FT                   /note="R -> G (in Ref. 1; CAH91929)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        70
FT                   /note="C -> Y (in Ref. 1; CAH91929)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   77 AA;  8764 MW;  1ECC27FF262E04B7 CRC64;
     MAPSALLRPV SRLLAPARLP SGRASARSKF YVREPLNAKP DWLKVGFTLG TTVFLWVYLI
     KQHNEDILEC KRRNGLE