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NDUC2_GORGO
ID   NDUC2_GORGO             Reviewed;         119 AA.
AC   Q0MQF8;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2 {ECO:0000250|UniProtKB:O95298};
DE   AltName: Full=Complex I-B14.5b;
DE            Short=CI-B14.5b;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.5b;
GN   Name=NDUFC2 {ECO:0000250|UniProtKB:O95298};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis but required for the complex assembly. Complex I
CC       functions in the transfer of electrons from NADH to the respiratory
CC       chain. The immediate electron acceptor for the enzyme is believed to be
CC       ubiquinone. {ECO:0000250|UniProtKB:O95298}.
CC   -!- SUBUNIT: Complex I is composed of 45 different subunits. Interacts with
CC       TMEM242 (By similarity). {ECO:0000250|UniProtKB:O95298}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O95298}; Single-pass membrane protein
CC       {ECO:0000255}; Matrix side {ECO:0000250|UniProtKB:O95298}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFC2 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; DQ885676; ABH12185.1; -; mRNA.
DR   RefSeq; NP_001266623.1; NM_001279694.1.
DR   AlphaFoldDB; Q0MQF8; -.
DR   SMR; Q0MQF8; -.
DR   STRING; 9593.ENSGGOP00000005070; -.
DR   PRIDE; Q0MQF8; -.
DR   Ensembl; ENSGGOT00000051336; ENSGGOP00000049658; ENSGGOG00000041901.
DR   GeneID; 101142450; -.
DR   KEGG; ggo:101142450; -.
DR   CTD; 4718; -.
DR   eggNOG; KOG4516; Eukaryota.
DR   GeneTree; ENSGT00390000010352; -.
DR   HOGENOM; CLU_156652_0_0_1; -.
DR   InParanoid; Q0MQF8; -.
DR   OMA; WFIGYHL; -.
DR   OrthoDB; 1606491at2759; -.
DR   Proteomes; UP000001519; Chromosome 11.
DR   Bgee; ENSGGOG00000041901; Expressed in testis and 5 other tissues.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; ISS:UniProtKB.
DR   InterPro; IPR009423; NDUC2.
DR   PANTHER; PTHR13099; PTHR13099; 1.
DR   Pfam; PF06374; NDUF_C2; 1.
DR   PIRSF; PIRSF017834; NADH-UbQ_OxRdtase_b14.5b; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   Reference proteome; Respiratory chain; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..119
FT                   /note="NADH dehydrogenase [ubiquinone] 1 subunit C2"
FT                   /id="PRO_0000251850"
FT   TRANSMEM        56..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   119 AA;  14188 MW;  9A47DEE33DC9244D CRC64;
     MIARRNPEPL RFLPDEARSL PPPKLTDPRL LYIGFLGYCS GLIDNLIRRR PIATAGLHRQ
     LLYITAFFFA GYYLVKREDY LYAVRDREMF GYMKLHPEDF PEEDKKTYGE IFEKFHPIR
 
 
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