NDUF3_BOVIN
ID NDUF3_BOVIN Reviewed; 184 AA.
AC Q2HJI2;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3;
GN Name=NDUFAF3;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential factor for the assembly of mitochondrial
CC NADH:ubiquinone oxidoreductase complex (complex I). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with NDUFAF4, NDUFS2 and NDUFS3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Mitochondrion inner
CC membrane {ECO:0000250}.
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DR EMBL; BC105350; AAI05351.1; -; mRNA.
DR RefSeq; NP_001039570.1; NM_001046105.2.
DR RefSeq; XP_005222834.1; XM_005222777.3.
DR RefSeq; XP_005222835.1; XM_005222778.2.
DR RefSeq; XP_005222836.1; XM_005222779.3.
DR RefSeq; XP_015315042.1; XM_015459556.1.
DR RefSeq; XP_015315043.1; XM_015459557.1.
DR RefSeq; XP_015315044.1; XM_015459558.1.
DR AlphaFoldDB; Q2HJI2; -.
DR SMR; Q2HJI2; -.
DR STRING; 9913.ENSBTAP00000025174; -.
DR PaxDb; Q2HJI2; -.
DR PRIDE; Q2HJI2; -.
DR Ensembl; ENSBTAT00000025174; ENSBTAP00000025174; ENSBTAG00000018918.
DR GeneID; 511968; -.
DR KEGG; bta:511968; -.
DR CTD; 25915; -.
DR VEuPathDB; HostDB:ENSBTAG00000018918; -.
DR VGNC; VGNC:31955; NDUFAF3.
DR eggNOG; KOG3363; Eukaryota.
DR GeneTree; ENSGT00390000018312; -.
DR HOGENOM; CLU_074390_3_1_1; -.
DR InParanoid; Q2HJI2; -.
DR OMA; FSKAYDH; -.
DR OrthoDB; 1569969at2759; -.
DR TreeFam; TF321072; -.
DR Reactome; R-BTA-6799198; Complex I biogenesis.
DR Proteomes; UP000009136; Chromosome 22.
DR Bgee; ENSBTAG00000018918; Expressed in retina and 106 other tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IBA:GO_Central.
DR CDD; cd05125; Mth938_2P1-like; 1.
DR Gene3D; 3.40.1230.10; -; 1.
DR InterPro; IPR036748; MTH938-like_sf.
DR InterPro; IPR034095; NDUF3.
DR InterPro; IPR007523; NDUFAF3/AAMDC.
DR PANTHER; PTHR21192; PTHR21192; 1.
DR Pfam; PF04430; DUF498; 1.
DR SUPFAM; SSF64076; SSF64076; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleus;
KW Reference proteome.
FT CHAIN 1..184
FT /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT assembly factor 3"
FT /id="PRO_0000281153"
SQ SEQUENCE 184 AA; 20477 MW; AC241749058C2D77 CRC64;
MAAAFVLRNL YRARPALRSP PSELPWAPRR GHRLTPADDE LYQRTRISLL QRESPLAMYI
DSYSSRGFVV NGNRVFGPCA LLPQSVVQWN VGSYQDITEE SFSLFWMLEP RIEIVVVGTG
DRTERLQPHV LRAMRQRGIA VEVQDTPNAC ATFNFLCHEG RVTGAALIPP PGGTALTSQA
QAAE