ID   NDUF3_DANRE             Reviewed;         174 AA.
AC   A1L1F1;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3;
GN   Name=ndufaf3; ORFNames=zgc:153176;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential factor for the assembly of mitochondrial
CC       NADH:ubiquinone oxidoreductase complex (complex I). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Mitochondrion inner
CC       membrane {ECO:0000250}.
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DR   EMBL; BC129030; AAI29031.1; -; mRNA.
DR   RefSeq; NP_001074084.1; NM_001080615.1.
DR   AlphaFoldDB; A1L1F1; -.
DR   SMR; A1L1F1; -.
DR   STRING; 7955.ENSDARP00000109973; -.
DR   PaxDb; A1L1F1; -.
DR   PeptideAtlas; A1L1F1; -.
DR   Ensembl; ENSDART00000161432; ENSDARP00000134881; ENSDARG00000112931.
DR   Ensembl; ENSDART00000184883; ENSDARP00000156172; ENSDARG00000112931.
DR   GeneID; 791133; -.
DR   KEGG; dre:791133; -.
DR   CTD; 25915; -.
DR   ZFIN; ZDB-GENE-070112-282; ndufaf3.
DR   eggNOG; KOG3363; Eukaryota.
DR   GeneTree; ENSGT00390000018312; -.
DR   InParanoid; A1L1F1; -.
DR   OrthoDB; 1569969at2759; -.
DR   PhylomeDB; A1L1F1; -.
DR   TreeFam; TF321072; -.
DR   Reactome; R-DRE-6799198; Complex I biogenesis.
DR   PRO; PR:A1L1F1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 22.
DR   Bgee; ENSDARG00000112931; Expressed in muscle tissue and 24 other tissues.
DR   ExpressionAtlas; A1L1F1; baseline.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IBA:GO_Central.
DR   CDD; cd05125; Mth938_2P1-like; 1.
DR   Gene3D; 3.40.1230.10; -; 1.
DR   InterPro; IPR036748; MTH938-like_sf.
DR   InterPro; IPR034095; NDUF3.
DR   InterPro; IPR007523; NDUFAF3/AAMDC.
DR   PANTHER; PTHR21192; PTHR21192; 1.
DR   Pfam; PF04430; DUF498; 1.
DR   SUPFAM; SSF64076; SSF64076; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..174
FT                   /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex
FT                   assembly factor 3"
FT                   /id="PRO_0000281156"
SQ   SEQUENCE   174 AA;  19019 MW;  9AA83FF235F638F4 CRC64;
     MAAVRHLCQR TAIRLRLTCS PQSRVCVVRG HRLGPFDDEQ YRKTSVSIMQ KEASAGTVIY
     SYSPRGFNIN GNTVFGPCAV LPPAILQWNV GSHSDISVES LSLFYLLEPQ IEVLVLGTGA
     RTERLHAEVL EELKKRGIAV EVQDTPNACA TFNFLSSEKR LAAAALIPPP AGSR