ID   NDUS3_MARPO             Reviewed;         195 AA.
AC   P34944;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3;
DE            EC=7.1.1.2;
DE   AltName: Full=NADH dehydrogenase subunit 9;
GN   Name=NAD9;
OS   Marchantia polymorpha (Liverwort) (Marchantia aquatica).
OG   Mitochondrion.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Marchantiophyta;
OC   Marchantiopsida; Marchantiidae; Marchantiales; Marchantiaceae; Marchantia.
OX   NCBI_TaxID=3197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1731062; DOI=10.1016/0022-2836(92)90708-r;
RA   Oda K., Yamato K., Ohta E., Nakamura Y., Takemura M., Nozato N., Akashi K.,
RA   Kanegae T., Ogura Y., Kohchi T., Ohyama K.;
RT   "Gene organization deduced from the complete sequence of liverwort
RT   Marchantia polymorpha mitochondrial DNA. A primitive form of plant
RT   mitochondrial genome.";
RL   J. Mol. Biol. 223:1-7(1992).
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain
CC       NADH dehydrogenase (Complex I) that is believed to belong to the
CC       minimal assembly required for catalysis. Complex I functions in the
CC       transfer of electrons from NADH to the respiratory chain. The immediate
CC       electron acceptor for the enzyme is believed to be ubiquinone (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) +
CC         NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA-
CC         COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2;
CC   -!- SUBUNIT: Complex I is composed of about 45 different subunits. This is
CC       a component of the iron-sulfur (IP) fragment of the enzyme (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane.
CC   -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC09443.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M68929; AAC09443.1; ALT_INIT; Genomic_DNA.
DR   PIR; S25996; S25996.
DR   RefSeq; NP_054446.1; NC_001660.1.
DR   AlphaFoldDB; P34944; -.
DR   SMR; P34944; -.
DR   GeneID; 2948426; -.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.460.80; -; 1.
DR   HAMAP; MF_01357; NDH1_NuoC; 1.
DR   InterPro; IPR010218; NADH_DH_suC.
DR   InterPro; IPR037232; NADH_quin_OxRdtase_su_C/D-like.
DR   InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR   InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR   Pfam; PF00329; Complex1_30kDa; 1.
DR   SUPFAM; SSF143243; SSF143243; 1.
DR   TIGRFAMs; TIGR01961; NuoC_fam; 1.
DR   PROSITE; PS00542; COMPLEX1_30K; 1.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW   NAD; Oxidoreductase; Respiratory chain; Translocase; Transport; Ubiquinone.
FT   CHAIN           1..195
FT                   /note="NADH dehydrogenase [ubiquinone] iron-sulfur protein
FT                   3"
FT                   /id="PRO_0000118641"
SQ   SEQUENCE   195 AA;  23354 MW;  D123890812812ABB CRC64;
     MDNQLFFKSL IATLPKWIHK CQTSKHENIL YTNPNSLFQL LYFLKYHTNT RFKVLIDICG
     VDYPSRKRRF EVVYNLLSID YNTRIRILTS VDEITPICSV VSIFPSAGWW ERETWDMFGV
     YFSNHPDLRR ILTDYGFEGH PLRKDFPLSG YVEVRYDDSE KRVVSEPIEM TQEFRYFDFA
     SPWEQMSRSD ESNQK