NDUS3_PROWI
ID NDUS3_PROWI Reviewed; 192 AA.
AC Q37622;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=NADH-ubiquinone oxidoreductase subunit 9;
DE EC=7.1.1.2;
GN Name=NAD9;
OS Prototheca wickerhamii.
OG Mitochondrion.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Trebouxiophyceae;
OC Chlorellales; Chlorellaceae; Prototheca.
OX NCBI_TaxID=3111;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=263-11;
RX PubMed=8133522; DOI=10.1006/jmbi.1994.1210;
RA Wolff G., Plante I., Lang B.F., Kueck U., Burger G.;
RT "Complete sequence of the mitochondrial DNA of the chlorophyte alga
RT Prototheca wickerhamii. Gene content and genome organization.";
RL J. Mol. Biol. 237:75-86(1994).
CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory chain
CC NADH dehydrogenase (Complex I) that is believed to belong to the
CC minimal assembly required for catalysis. Complex I functions in the
CC transfer of electrons from NADH to the respiratory chain. The immediate
CC electron acceptor for the enzyme is believed to be ubiquinone (By
CC similarity). {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) +
CC NAD(+); Xref=Rhea:RHEA:29091, Rhea:RHEA-COMP:9565, Rhea:RHEA-
CC COMP:9566, ChEBI:CHEBI:15378, ChEBI:CHEBI:16389, ChEBI:CHEBI:17976,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=7.1.1.2;
CC -!- SUBUNIT: Complex I is composed of about 30 different subunits.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC Note=Matrix and cytoplasmic side of the mitochondrial inner membrane.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U02970; AAD12649.1; -; Genomic_DNA.
DR PIR; T11930; T11930.
DR RefSeq; NP_042261.1; NC_001613.1.
DR AlphaFoldDB; Q37622; -.
DR SMR; Q37622; -.
DR GeneID; 802143; -.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.460.80; -; 1.
DR HAMAP; MF_01357; NDH1_NuoC; 1.
DR InterPro; IPR010218; NADH_DH_suC.
DR InterPro; IPR037232; NADH_quin_OxRdtase_su_C/D-like.
DR InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su.
DR InterPro; IPR020396; NADH_UbQ_OxRdtase_CS.
DR Pfam; PF00329; Complex1_30kDa; 1.
DR SUPFAM; SSF143243; SSF143243; 1.
DR TIGRFAMs; TIGR01961; NuoC_fam; 1.
DR PROSITE; PS00542; COMPLEX1_30K; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW NAD; Oxidoreductase; Respiratory chain; Translocase; Transport; Ubiquinone.
FT CHAIN 1..192
FT /note="NADH-ubiquinone oxidoreductase subunit 9"
FT /id="PRO_0000118648"
SQ SEQUENCE 192 AA; 23204 MW; F04204944207582D CRC64;
MNNNFEKSIL LMVPQWIQYH VSHRNETTFY VYPEYLKPFL YFLRDHMSTQ YKVCIDITAA
DYPSRASRFE CVYNLLSVEY NSRIRIKTCV DEITTLESVT PVYSSAAWWE REVWDMFGVF
FHNHPDLRRI LTDYGFQGHP LRKDFPLSGY VEVRYDDSEK RVCIESVEYS QEFRYFDFES
PWEQVDKNSL LK