NDUS6_CAEEL
ID NDUS6_CAEEL Reviewed; 140 AA.
AC Q19724;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial;
DE AltName: Full=Complex I-13kD-A;
DE Short=CI-13kD-A;
DE AltName: Full=NADH-ubiquinone oxidoreductase 13 kDa-A subunit;
DE Flags: Precursor;
GN Name=nduf-6; ORFNames=F22D6.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits. This is a
CC component of the iron-sulfur (IP) fragment of the enzyme (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the complex I NDUFS6 subunit family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z71262; CAA95810.1; -; Genomic_DNA.
DR PIR; T21255; T21255.
DR RefSeq; NP_492007.1; NM_059606.6.
DR AlphaFoldDB; Q19724; -.
DR SMR; Q19724; -.
DR BioGRID; 49611; 49.
DR IntAct; Q19724; 1.
DR STRING; 6239.F22D6.4.2; -.
DR EPD; Q19724; -.
DR PaxDb; Q19724; -.
DR PeptideAtlas; Q19724; -.
DR EnsemblMetazoa; F22D6.4.1; F22D6.4.1; WBGene00009051.
DR GeneID; 184827; -.
DR KEGG; cel:CELE_F22D6.4; -.
DR CTD; 184827; -.
DR WormBase; F22D6.4; CE05685; WBGene00009051; nduf-6.
DR eggNOG; KOG3456; Eukaryota.
DR GeneTree; ENSGT00390000015775; -.
DR HOGENOM; CLU_083053_3_0_1; -.
DR InParanoid; Q19724; -.
DR OMA; RFYNSHV; -.
DR OrthoDB; 1641902at2759; -.
DR PhylomeDB; Q19724; -.
DR SignaLink; Q19724; -.
DR PRO; PR:Q19724; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00009051; Expressed in material anatomical entity and 5 other tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; HDA:WormBase.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IMP:WormBase.
DR GO; GO:0009410; P:response to xenobiotic stimulus; IMP:WormBase.
DR InterPro; IPR016668; NDUFS6.
DR InterPro; IPR019401; Znf_CHCC.
DR Pfam; PF10276; zf-CHCC; 1.
DR PIRSF; PIRSF016564; CI-13KD-A; 1.
PE 3: Inferred from homology;
KW Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Respiratory chain; Transit peptide; Transport.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN ?..140
FT /note="Probable NADH dehydrogenase [ubiquinone] iron-sulfur
FT protein 6, mitochondrial"
FT /id="PRO_0000020022"
SQ SEQUENCE 140 AA; 15656 MW; 16586DD102F954EE CRC64;
MNRLLQQSVS RGPLAVRASS TITTKPPTPN QITKNNAQFD KVTHTGQAWD QSDYRLQRFD
ISKKSVNPNV AMHLIDQRPP EDCGDKRVVF CDGGHPALGH PKVYINLDKP GVHACGYCGN
RFYNSHATKA EDMKIQHLNC
