ID   NDUS6_GORGO             Reviewed;         124 AA.
AC   Q0MQH6;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial;
DE   AltName: Full=Complex I-13kD-A;
DE            Short=CI-13kD-A;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 13 kDa-A subunit;
DE   Flags: Precursor;
GN   Name=NDUFS6;
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O75380}.
CC   -!- SUBUNIT: Mammalian complex I is composed of 45 different subunits. This
CC       is a component of the iron-sulfur (IP) fragment of the enzyme.
CC       {ECO:0000250|UniProtKB:O75380}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O75380}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:O75380}; Matrix side
CC       {ECO:0000250|UniProtKB:O75380}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFS6 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; DQ885658; ABH12167.1; -; mRNA.
DR   RefSeq; NP_001266642.1; NM_001279713.1.
DR   AlphaFoldDB; Q0MQH6; -.
DR   SMR; Q0MQH6; -.
DR   STRING; 9593.ENSGGOP00000016543; -.
DR   Ensembl; ENSGGOT00000017008; ENSGGOP00000016543; ENSGGOG00000016951.
DR   GeneID; 101151434; -.
DR   KEGG; ggo:101151434; -.
DR   CTD; 4726; -.
DR   eggNOG; KOG3456; Eukaryota.
DR   GeneTree; ENSGT00390000015775; -.
DR   HOGENOM; CLU_083053_3_2_1; -.
DR   InParanoid; Q0MQH6; -.
DR   OMA; VRFVNAK; -.
DR   OrthoDB; 1641902at2759; -.
DR   Proteomes; UP000001519; Chromosome 17.
DR   Bgee; ENSGGOG00000016951; Expressed in heart and 5 other tissues.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IBA:GO_Central.
DR   InterPro; IPR016668; NDUFS6.
DR   InterPro; IPR019401; Znf_CHCC.
DR   Pfam; PF10276; zf-CHCC; 1.
DR   PIRSF; PIRSF016564; CI-13KD-A; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Reference proteome; Respiratory chain;
KW   Transit peptide; Transport.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           29..124
FT                   /note="NADH dehydrogenase [ubiquinone] iron-sulfur protein
FT                   6, mitochondrial"
FT                   /id="PRO_0000251868"
FT   MOD_RES         98
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P52503"
SQ   SEQUENCE   124 AA;  13731 MW;  1FF465160BCA772D CRC64;
     MAAAMTFCRL LNRCGEAARS LPLGARCFGV RVSPTGEKVT HTGQVYDDKD YRRIRFVGRQ
     KEVNENFAID LIAEQPVSEV ETRVIACDGG GGALGHPKVY INLDKETKTG TCGYCGLQFR
     QHHR