ID   NDUS6_PONPY             Reviewed;         124 AA.
AC   Q0MQH5;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial;
DE   AltName: Full=Complex I-13kD-A;
DE            Short=CI-13kD-A;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 13 kDa-A subunit;
DE   Flags: Precursor;
GN   Name=NDUFS6;
OS   Pongo pygmaeus (Bornean orangutan).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16828987; DOI=10.1016/j.gene.2006.03.015;
RA   Mishmar D., Ruiz-Pesini E., Mondragon-Palomino M., Procaccio V., Gaut B.,
RA   Wallace D.C.;
RT   "Adaptive selection of mitochondrial complex I subunits during primate
RT   radiation.";
RL   Gene 378:11-18(2006).
CC   -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I), that is believed not to be
CC       involved in catalysis. Complex I functions in the transfer of electrons
CC       from NADH to the respiratory chain. The immediate electron acceptor for
CC       the enzyme is believed to be ubiquinone.
CC       {ECO:0000250|UniProtKB:O75380}.
CC   -!- SUBUNIT: Mammalian complex I is composed of 45 different subunits. This
CC       is a component of the iron-sulfur (IP) fragment of the enzyme.
CC       {ECO:0000250|UniProtKB:O75380}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:O75380}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:O75380}; Matrix side
CC       {ECO:0000250|UniProtKB:O75380}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFS6 subunit family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ885659; ABH12168.1; -; mRNA.
DR   AlphaFoldDB; Q0MQH5; -.
DR   SMR; Q0MQH5; -.
DR   GO; GO:0005747; C:mitochondrial respiratory chain complex I; ISS:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   InterPro; IPR016668; NDUFS6.
DR   InterPro; IPR019401; Znf_CHCC.
DR   Pfam; PF10276; zf-CHCC; 1.
DR   PIRSF; PIRSF016564; CI-13KD-A; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; Respiratory chain; Transit peptide;
KW   Transport.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           29..124
FT                   /note="NADH dehydrogenase [ubiquinone] iron-sulfur protein
FT                   6, mitochondrial"
FT                   /id="PRO_0000251870"
FT   MOD_RES         98
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P52503"
SQ   SEQUENCE   124 AA;  13914 MW;  EF002E530D91A98F CRC64;
     MAAAMTFYRL LNRWGEAARS LRLGARCFGV RVSPTGEKVT HTGQVYDDKD YRRIRFVGRQ
     KEVNENFAID LIAEQPVSEV ETRVIACDGG GGALGHPKVY INLDKETKTG TCGYCGLQFR
     QHHH