NDUV3_HUMAN
ID NDUV3_HUMAN Reviewed; 108 AA.
AC P56181; A8K0M1; J3KNX7; Q6FGD3; Q8WU60; Q9HCR5;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2002, sequence version 2.
DT 03-AUG-2022, entry version 170.
DE RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial;
DE AltName: Full=Complex I-9kD;
DE Short=CI-9kD;
DE AltName: Full=NADH-ubiquinone oxidoreductase 9 kDa subunit;
DE AltName: Full=Renal carcinoma antigen NY-REN-4;
DE Flags: Precursor;
GN Name=NDUFV3;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9344673; DOI=10.1006/geno.1997.4930;
RA de Coo R.F.M., Buddiger P., Smeets H.J.M., van Oost B.A.;
RT "Molecular cloning and characterization of the human mitochondrial
RT NADH:oxidoreductase 10-kDa gene (NDUFV3).";
RL Genomics 45:434-437(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10950923; DOI=10.1006/geno.2000.6253;
RA Berry A., Scott H.S., Kudoh J., Talior I., Korostishevsky M.,
RA Wattenhofer M., Guipponi M., Barras C., Rossier C., Shibuya K., Wang J.,
RA Kawasaki K., Asakawa S., Minoshima S., Shimizu N., Antonarakis S.E.,
RA Bonne-Tamir B.;
RT "Refined localization of autosomal recessive nonsyndromic deafness DFNB10
RT locus using 34 novel microsatellite markers, genomic structure, and
RT exclusion of six known genes in the region.";
RL Genomics 68:22-29(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P.,
RA Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y.,
RA LaBaer J.;
RT "Cloning of human full open reading frames in Gateway(TM) system entry
RT vector (pDONR201).";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Cerebellum;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10830953; DOI=10.1038/35012518;
RA Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S.,
RA Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M.,
RA Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A., Menzel U.,
RA Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A.,
RA Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J.,
RA Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K.,
RA Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G.,
RA Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J.,
RA Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S.,
RA Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K.,
RA Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.;
RT "The DNA sequence of human chromosome 21.";
RL Nature 405:311-319(2000).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Brain, and Uterus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [8]
RP IDENTIFICATION AS A RENAL CANCER ANTIGEN.
RC TISSUE=Renal cell carcinoma;
RX PubMed=10508479;
RX DOI=10.1002/(sici)1097-0215(19991112)83:4<456::aid-ijc4>3.0.co;2-5;
RA Scanlan M.J., Gordan J.D., Williamson B., Stockert E., Bander N.H.,
RA Jongeneel C.V., Gure A.O., Jaeger D., Jaeger E., Knuth A., Chen Y.-T.,
RA Old L.J.;
RT "Antigens recognized by autologous antibody in patients with renal-cell
RT carcinoma.";
RL Int. J. Cancer 83:456-464(1999).
RN [9]
RP IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX,
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX PubMed=12611891; DOI=10.1074/jbc.c300064200;
RA Murray J., Zhang B., Taylor S.W., Oglesbee D., Fahy E., Marusich M.F.,
RA Ghosh S.S., Capaldi R.A.;
RT "The subunit composition of the human NADH dehydrogenase obtained by rapid
RT one-step immunopurification.";
RL J. Biol. Chem. 278:13619-13622(2003).
RN [10]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=18691976; DOI=10.1016/j.molcel.2008.07.007;
RA Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R.,
RA Greff Z., Keri G., Stemmann O., Mann M.;
RT "Kinase-selective enrichment enables quantitative phosphoproteomics of the
RT kinome across the cell cycle.";
RL Mol. Cell 31:438-448(2008).
RN [11]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-160; SER-162 AND SER-164
RP (ISOFORM 2), AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE
RP ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=18669648; DOI=10.1073/pnas.0805139105;
RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,
RA Elledge S.J., Gygi S.P.;
RT "A quantitative atlas of mitotic phosphorylation.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
RN [12]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Leukemic T-cell;
RX PubMed=19690332; DOI=10.1126/scisignal.2000007;
RA Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,
RA Rodionov V., Han D.K.;
RT "Quantitative phosphoproteomic analysis of T cell receptor signaling
RT reveals system-wide modulation of protein-protein interactions.";
RL Sci. Signal. 2:RA46-RA46(2009).
RN [13]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma;
RX PubMed=20068231; DOI=10.1126/scisignal.2000475;
RA Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L.,
RA Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.;
RT "Quantitative phosphoproteomics reveals widespread full phosphorylation
RT site occupancy during mitosis.";
RL Sci. Signal. 3:RA3-RA3(2010).
RN [14]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21406692; DOI=10.1126/scisignal.2001570;
RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T.,
RA Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.;
RT "System-wide temporal characterization of the proteome and phosphoproteome
RT of human embryonic stem cell differentiation.";
RL Sci. Signal. 4:RS3-RS3(2011).
RN [15]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-105, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Cervix carcinoma, and Erythroleukemia;
RX PubMed=23186163; DOI=10.1021/pr300630k;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
RN [16]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-162 AND SER-164 (ISOFORM 2),
RP AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L.,
RA Ye M., Zou H.;
RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver
RT phosphoproteome.";
RL J. Proteomics 96:253-262(2014).
RN [17]
RP FUNCTION, AND IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX.
RX PubMed=27626371; DOI=10.1038/nature19754;
RA Stroud D.A., Surgenor E.E., Formosa L.E., Reljic B., Frazier A.E.,
RA Dibley M.G., Osellame L.D., Stait T., Beilharz T.H., Thorburn D.R.,
RA Salim A., Ryan M.T.;
RT "Accessory subunits are integral for assembly and function of human
RT mitochondrial complex I.";
RL Nature 538:123-126(2016).
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone. May be the terminally
CC assembled subunit of Complex I. {ECO:0000269|PubMed:27626371}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits. This is a
CC component of the flavoprotein-sulfur (FP) fragment of the enzyme.
CC {ECO:0000269|PubMed:12611891, ECO:0000269|PubMed:27626371}.
CC -!- INTERACTION:
CC P56181; P49821: NDUFV1; NbExp=2; IntAct=EBI-721902, EBI-748312;
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000305|PubMed:12611891}; Peripheral membrane protein
CC {ECO:0000305}; Matrix side {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=P56181-1; Sequence=Displayed;
CC Name=2;
CC IsoId=P56181-2; Sequence=VSP_038552;
CC -!- SIMILARITY: Belongs to the complex I NDUFV3 subunit family.
CC {ECO:0000305}.
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DR EMBL; X99726; CAB56704.1; -; Genomic_DNA.
DR EMBL; X99727; CAB56704.1; JOINED; Genomic_DNA.
DR EMBL; X99728; CAB56704.1; JOINED; Genomic_DNA.
DR EMBL; AB038163; BAB13732.1; -; Genomic_DNA.
DR EMBL; CR542174; CAG46971.1; -; mRNA.
DR EMBL; CR542190; CAG46987.1; -; mRNA.
DR EMBL; AK289586; BAF82275.1; -; mRNA.
DR EMBL; AP001629; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471079; EAX09524.1; -; Genomic_DNA.
DR EMBL; CH471079; EAX09526.1; -; Genomic_DNA.
DR EMBL; BC021217; AAH21217.2; -; mRNA.
DR EMBL; BC033766; AAH33766.1; -; mRNA.
DR EMBL; BC054016; AAH54016.1; -; mRNA.
DR CCDS; CCDS33572.1; -. [P56181-2]
DR CCDS; CCDS33573.1; -. [P56181-1]
DR RefSeq; NP_001001503.1; NM_001001503.1. [P56181-1]
DR RefSeq; NP_066553.3; NM_021075.3. [P56181-2]
DR PDB; 5XTB; EM; 3.40 A; K=74-106.
DR PDB; 5XTD; EM; 3.70 A; K=74-106.
DR PDB; 5XTH; EM; 3.90 A; K=74-106.
DR PDB; 5XTI; EM; 17.40 A; BK/K=74-106.
DR PDBsum; 5XTB; -.
DR PDBsum; 5XTD; -.
DR PDBsum; 5XTH; -.
DR PDBsum; 5XTI; -.
DR AlphaFoldDB; P56181; -.
DR SMR; P56181; -.
DR BioGRID; 110809; 194.
DR ComplexPortal; CPX-577; Mitochondrial respiratory chain complex I.
DR CORUM; P56181; -.
DR IntAct; P56181; 48.
DR MINT; P56181; -.
DR STRING; 9606.ENSP00000346196; -.
DR BindingDB; P56181; -.
DR ChEMBL; CHEMBL2363065; -.
DR DrugBank; DB00157; NADH.
DR DrugBank; DB09270; Ubidecarenone.
DR DrugCentral; P56181; -.
DR iPTMnet; P56181; -.
DR PhosphoSitePlus; P56181; -.
DR BioMuta; NDUFV3; -.
DR EPD; P56181; -.
DR jPOST; P56181; -.
DR MassIVE; P56181; -.
DR MaxQB; P56181; -.
DR PaxDb; P56181; -.
DR PeptideAtlas; P56181; -.
DR PRIDE; P56181; -.
DR ProteomicsDB; 56899; -. [P56181-1]
DR ProteomicsDB; 56900; -. [P56181-2]
DR TopDownProteomics; P56181-1; -. [P56181-1]
DR Antibodypedia; 9794; 158 antibodies from 27 providers.
DR DNASU; 4731; -.
DR Ensembl; ENST00000340344.4; ENSP00000342895.3; ENSG00000160194.18. [P56181-1]
DR Ensembl; ENST00000354250.7; ENSP00000346196.2; ENSG00000160194.18. [P56181-2]
DR GeneID; 4731; -.
DR KEGG; hsa:4731; -.
DR MANE-Select; ENST00000354250.7; ENSP00000346196.2; NM_021075.4; NP_066553.3. [P56181-2]
DR UCSC; uc002zcm.4; human. [P56181-1]
DR CTD; 4731; -.
DR DisGeNET; 4731; -.
DR GeneCards; NDUFV3; -.
DR HGNC; HGNC:7719; NDUFV3.
DR HPA; ENSG00000160194; Tissue enhanced (skeletal).
DR MIM; 602184; gene.
DR neXtProt; NX_P56181; -.
DR OpenTargets; ENSG00000160194; -.
DR PharmGKB; PA31529; -.
DR VEuPathDB; HostDB:ENSG00000160194; -.
DR eggNOG; ENOG502S46A; Eukaryota.
DR GeneTree; ENSGT00390000012196; -.
DR HOGENOM; CLU_045834_0_0_1; -.
DR InParanoid; P56181; -.
DR OMA; FTFHDYV; -.
DR OrthoDB; 1132013at2759; -.
DR PhylomeDB; P56181; -.
DR TreeFam; TF338771; -.
DR BioCyc; MetaCyc:HS08459-MON; -.
DR PathwayCommons; P56181; -.
DR Reactome; R-HSA-611105; Respiratory electron transport.
DR Reactome; R-HSA-6799198; Complex I biogenesis.
DR SignaLink; P56181; -.
DR SIGNOR; P56181; -.
DR BioGRID-ORCS; 4731; 7 hits in 1084 CRISPR screens.
DR ChiTaRS; NDUFV3; human.
DR GeneWiki; NDUFV3; -.
DR GenomeRNAi; 4731; -.
DR Pharos; P56181; Tclin.
DR PRO; PR:P56181; -.
DR Proteomes; UP000005640; Chromosome 21.
DR RNAct; P56181; protein.
DR Bgee; ENSG00000160194; Expressed in left ventricle myocardium and 190 other tissues.
DR Genevisible; P56181; HS.
DR GO; GO:0005743; C:mitochondrial inner membrane; IDA:ComplexPortal.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IDA:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; IDA:HPA.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; TAS:ProtInc.
DR GO; GO:0003723; F:RNA binding; HDA:UniProtKB.
DR GO; GO:0009060; P:aerobic respiration; IC:ComplexPortal.
DR GO; GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IMP:CAFA.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; TAS:ProtInc.
DR GO; GO:0042776; P:proton motive force-driven mitochondrial ATP synthesis; IC:ComplexPortal.
DR InterPro; IPR026193; NDUFV3.
DR PANTHER; PTHR17117; PTHR17117; 2.
DR Pfam; PF15880; NDUFV3; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Electron transport; Membrane;
KW Mitochondrion; Mitochondrion inner membrane; Phosphoprotein;
KW Reference proteome; Respiratory chain; Transit peptide; Transport.
FT TRANSIT 1..34
FT /note="Mitochondrion"
FT /evidence="ECO:0000250"
FT CHAIN 35..108
FT /note="NADH dehydrogenase [ubiquinone] flavoprotein 3,
FT mitochondrial"
FT /id="PRO_0000020025"
FT REGION 33..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 105
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:23186163"
FT VAR_SEQ 56..57
FT /note="KK -> KNVVEPKERGKLLATQTAAELSKNLSSPSSYPPAVNKGRKVASPSP
FT SGSVLFTDEGVPKFLSRKTLVEFPQKVLSPFRKQGSDSEARQVGRKVTSPSSSSSSSSS
FT DSESDDEADVSEVTPRVVSKGRGGLRKPEASHSFENRAPRVTVSAKEKTLLQKPHVDIT
FT DPEKPHQPKKKGSPAKPSEGRENARPKTTMPRSQVDEEFLKQSLKEKQLQKTFRLNEID
FT KESQKPFEVKGPLPVHTKSGLSAPPKGSPAPAVLAEEARAEGQLQASPPGAAEGHLEKP
FT VPEPQRKAAPPLPRKETSGTQGIEGHLKGGQAIVEDQIPPSNLETVPVENNHGFHEKTA
FT ALKLEAEGEAMEDAAAPGDDRGGTQE (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334"
FT /id="VSP_038552"
FT CONFLICT 9
FT /note="Q -> K (in Ref. 1; CAB56704)"
FT /evidence="ECO:0000305"
FT HELIX 83..90
FT /evidence="ECO:0007829|PDB:5XTB"
FT HELIX 91..94
FT /evidence="ECO:0007829|PDB:5XTB"
FT MOD_RES P56181-2:160
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18669648"
FT MOD_RES P56181-2:162
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18669648,
FT ECO:0007744|PubMed:24275569"
FT MOD_RES P56181-2:164
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18669648,
FT ECO:0007744|PubMed:24275569"
FT CONFLICT P56181-2:415
FT /note="D -> N (in Ref. 7; AAH21217)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 108 AA; 11941 MW; BD7375474AB0B1EC CRC64;
MAAPCLLRQG RAGALKTMLQ EAQVFRGLAS TVSLSAESGK SEKGQPQNSK KQSPPKKPAP
VPAEPFDNTT YKNLQHHDYS TYTFLDLNLE LSKFRMPQPS SGRESPRH
