ID   NDX7_CAEEL              Reviewed;         295 AA.
AC   P91148;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Putative nudix hydrolase 7;
DE            EC=3.6.1.-;
GN   Name=ndx-7; ORFNames=C43E11.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Probably mediates the hydrolysis of some nucleoside
CC       diphosphate derivatives. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. {ECO:0000305}.
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DR   EMBL; FO080612; CCD65159.1; -; Genomic_DNA.
DR   PIR; F87753; F87753.
DR   RefSeq; NP_491336.2; NM_058935.6.
DR   AlphaFoldDB; P91148; -.
DR   SMR; P91148; -.
DR   BioGRID; 48240; 3.
DR   STRING; 6239.C43E11.7; -.
DR   EPD; P91148; -.
DR   PaxDb; P91148; -.
DR   PeptideAtlas; P91148; -.
DR   EnsemblMetazoa; C43E11.7.1; C43E11.7.1; WBGene00003584.
DR   GeneID; 183413; -.
DR   KEGG; cel:CELE_C43E11.7; -.
DR   UCSC; C43E11.7.1; c. elegans.
DR   CTD; 183413; -.
DR   WormBase; C43E11.7; CE30504; WBGene00003584; ndx-7.
DR   eggNOG; KOG3904; Eukaryota.
DR   GeneTree; ENSGT00420000029858; -.
DR   HOGENOM; CLU_1062590_0_0_1; -.
DR   InParanoid; P91148; -.
DR   OMA; HETVFFM; -.
DR   OrthoDB; 1417901at2759; -.
DR   PhylomeDB; P91148; -.
DR   Reactome; R-CEL-390918; Peroxisomal lipid metabolism.
DR   Reactome; R-CEL-9033241; Peroxisomal protein import.
DR   PRO; PR:P91148; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00003584; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   InterPro; IPR039121; NUDT19.
DR   PANTHER; PTHR12318; PTHR12318; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
DR   PROSITE; PS51462; NUDIX; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Manganese; Metal-binding; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Putative nudix hydrolase 7"
FT                   /id="PRO_0000057137"
FT   DOMAIN          9..182
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00794"
FT   MOTIF           52..73
FT                   /note="Nudix box"
FT   BINDING         67
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         71
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   295 AA;  33500 MW;  B2005132EC827147 CRC64;
     MCIGKVTSSW RSAASIILAC KTTRRVLMLK RGTTAKFMPN TMVFPGGVVD KTDAKLGDEF
     RIAAVRELFE ESGVLSTKNG WQTSANNPDM TSLKADIVND TSKFEQLSGT ICADNLIEWD
     TFITPANYPR RFLTKFYLML VDDEPAIDLC TSEMSEYNWI EPKECVDEAY AGKYALPPPQ
     VYELTRLSQV KDWDLCEKYG NVKKPICPQP IKTIGENLIT NCFPGDYMYI DENSLQQPLR
     QMSADRVTVD PTQPTHRATY YSEPMYGKVR LYQHLLKPAD IAAFHQFDTH SKDLL