ID   NEMS_CAMFO              Reviewed;          94 AA.
AC   E2A3M7;
DT   14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   25-MAY-2022, entry version 21.
DE   RecName: Full=Myosuppressin {ECO:0000303|PubMed:25641051};
DE   Flags: Precursor;
GN   ORFNames=EAG_03924 {ECO:0000312|EMBL:EFN71919.1};
OS   Camponotus floridanus (Florida carpenter ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Formicinae; Camponotus.
OX   NCBI_TaxID=104421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20798317; DOI=10.1126/science.1192428;
RA   Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G.,
RA   Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D.,
RA   Wang J., Liebig J.;
RT   "Genomic comparison of the ants Camponotus floridanus and Harpegnathos
RT   saltator.";
RL   Science 329:1068-1071(2010).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 81-90, TISSUE SPECIFICITY, MASS SPECTROMETRY,
RP   IDENTIFICATION BY MASS SPECTROMETRY, AMIDATION AT PHE-90, AND PYROGLUTAMATE
RP   FORMATION AT GLN-81.
RX   PubMed=25641051; DOI=10.1021/pr5011636;
RA   Schmitt F., Vanselow J.T., Schlosser A., Kahnt J., Roessler W., Wegener C.;
RT   "Neuropeptidomics of the carpenter ant Camponotus floridanus.";
RL   J. Proteome Res. 14:1504-1514(2015).
CC   -!- FUNCTION: Myoinhibiting neuropeptide. {ECO:0000250|UniProtKB:P61849}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:25641051}.
CC   -!- TISSUE SPECIFICITY: Expressed throughout the nervous system (at protein
CC       level). {ECO:0000269|PubMed:25641051}.
CC   -!- MASS SPECTROMETRY: Mass=1257.63; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:25641051};
CC   -!- SIMILARITY: Belongs to the myosuppressin family. {ECO:0000305}.
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DR   EMBL; GL436457; EFN71919.1; -; Genomic_DNA.
DR   RefSeq; XP_011250951.1; XM_011252649.2.
DR   AlphaFoldDB; E2A3M7; -.
DR   STRING; 104421.E2A3M7; -.
DR   GeneID; 105248075; -.
DR   KEGG; cfo:105248075; -.
DR   InParanoid; E2A3M7; -.
DR   OMA; DAREMND; -.
DR   OrthoDB; 1636503at2759; -.
DR   Proteomes; UP000000311; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Cleavage on pair of basic residues; Direct protein sequencing;
KW   Neuropeptide; Pyrrolidone carboxylic acid; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   PROPEP          25..80
FT                   /evidence="ECO:0000305|PubMed:25641051"
FT                   /id="PRO_0000434222"
FT   PEPTIDE         81..90
FT                   /note="Myosuppressin"
FT                   /evidence="ECO:0000269|PubMed:25641051"
FT                   /id="PRO_0000434223"
FT   MOD_RES         81
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:25641051"
FT   MOD_RES         90
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:25641051"
SQ   SEQUENCE   94 AA;  10997 MW;  7141C009DC01EE5F CRC64;
     MMSPTLMILI SITTMAILSG ESFGAMPAQC NSEFLEELPP RLRKICVAIA RIWDAREMND
     FVDDREYREN LPRYDSSVKR QDVDHVFLRF GKRR