NET1B_ARATH
ID NET1B_ARATH Reviewed; 1710 AA.
AC F4JIF4; O23332;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Protein NETWORKED 1B {ECO:0000303|PubMed:22840520};
GN Name=NET1B {ECO:0000303|PubMed:22840520};
GN OrderedLocusNames=At4g14760 {ECO:0000312|Araport:AT4G14760};
GN ORFNames=dl3420w {ECO:0000312|EMBL:CAB10255.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=22840520; DOI=10.1016/j.cub.2012.06.041;
RA Deeks M.J., Calcutt J.R., Ingle E.K., Hawkins T.J., Chapman S.,
RA Richardson A.C., Mentlak D.A., Dixon M.R., Cartwright F., Smertenko A.P.,
RA Oparka K., Hussey P.J.;
RT "A superfamily of actin-binding proteins at the actin-membrane nexus of
RT higher plants.";
RL Curr. Biol. 22:1595-1600(2012).
RN [5]
RP GENE FAMILY.
RX PubMed=24926301; DOI=10.3389/fpls.2014.00254;
RA Hawkins T.J., Deeks M.J., Wang P., Hussey P.J.;
RT "The evolution of the actin binding NET superfamily.";
RL Front. Plant Sci. 5:254-254(2014).
CC -!- FUNCTION: Plant-specific actin binding protein. May be part of a
CC membrane-cytoskeletal adapter complex. {ECO:0000305|PubMed:22840520}.
CC -!- TISSUE SPECIFICITY: Expressed in root meristems and at very low levels
CC throughout mature vasculature. {ECO:0000269|PubMed:22840520}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype, due to the redundancy with
CC NET1A. Net1a and net1b double mutant shows a significant acceleration
CC in root-cell expansion. {ECO:0000269|PubMed:22840520}.
CC -!- SIMILARITY: Belongs to the NET family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB10255.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78518.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; Z97337; CAB10255.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161539; CAB78518.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83495.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM67769.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM67770.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM67771.1; -; Genomic_DNA.
DR PIR; E71410; E71410.
DR RefSeq; NP_001329577.1; NM_001340969.1.
DR RefSeq; NP_001329578.1; NM_001340968.1.
DR RefSeq; NP_001329579.1; NM_001340967.1.
DR RefSeq; NP_193212.4; NM_117561.6.
DR AlphaFoldDB; F4JIF4; -.
DR SMR; F4JIF4; -.
DR STRING; 3702.AT4G14760.1; -.
DR iPTMnet; F4JIF4; -.
DR PaxDb; F4JIF4; -.
DR PRIDE; F4JIF4; -.
DR ProteomicsDB; 249377; -.
DR EnsemblPlants; AT4G14760.1; AT4G14760.1; AT4G14760.
DR EnsemblPlants; AT4G14760.2; AT4G14760.2; AT4G14760.
DR EnsemblPlants; AT4G14760.3; AT4G14760.3; AT4G14760.
DR EnsemblPlants; AT4G14760.4; AT4G14760.4; AT4G14760.
DR GeneID; 827131; -.
DR Gramene; AT4G14760.1; AT4G14760.1; AT4G14760.
DR Gramene; AT4G14760.2; AT4G14760.2; AT4G14760.
DR Gramene; AT4G14760.3; AT4G14760.3; AT4G14760.
DR Gramene; AT4G14760.4; AT4G14760.4; AT4G14760.
DR KEGG; ath:AT4G14760; -.
DR Araport; AT4G14760; -.
DR TAIR; locus:2130210; AT4G14760.
DR eggNOG; ENOG502QQ6M; Eukaryota.
DR HOGENOM; CLU_001229_1_1_1; -.
DR InParanoid; F4JIF4; -.
DR OMA; EAPHREW; -.
DR OrthoDB; 60151at2759; -.
DR PRO; PR:F4JIF4; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; F4JIF4; baseline and differential.
DR Genevisible; F4JIF4; AT.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR InterPro; IPR011684; NAB.
DR Pfam; PF07765; KIP1; 1.
DR PROSITE; PS51774; NAB; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1710
FT /note="Protein NETWORKED 1B"
FT /id="PRO_0000431850"
FT DOMAIN 13..92
FT /note="NAB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01110"
FT REGION 113..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1409..1448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 152..446
FT /evidence="ECO:0000255"
FT COILED 474..546
FT /evidence="ECO:0000255"
FT COILED 579..883
FT /evidence="ECO:0000255"
FT COILED 974..1021
FT /evidence="ECO:0000255"
FT COILED 1095..1259
FT /evidence="ECO:0000255"
FT COILED 1285..1336
FT /evidence="ECO:0000255"
FT COILED 1559..1665
FT /evidence="ECO:0000255"
SQ SEQUENCE 1710 AA; 196978 MW; 45A2EBDA58BA6AC5 CRC64;
MASLSQSESG RLYSWWWDSH IPKNSKWIQD NLADMDSKVK TMIKLIEADA DSFARRADMY
FKKRPELMKL VEELYRAYRA LAERYDHTTV ELRRAHKVMV EAFPNQMSFD MIEDSASSSS
EPRTEADTEA LQKDGTKSKR SFSQMNKLDG TSDSHEADSE VETLKRTLLE LQTEKEALNL
QYQLILSKVS RFEKELNDAQ KDVKGFDERA CKADIEIKIL KESLAKLEVE RDTGLLQYSQ
AIERIADLEA SISHGQEYAK GLTNRVSEAE REAMSLKKEL SRLQSEKEAG LLRYNKSLEL
ISSLEKTIRD AEESVRVFRD QSEQAETEIK ALKQELLKLN EVNEDLNVRY QQCLETISKL
EREVSHAQDN AKRLSSEVLA GAAKIKTVEE QCALLESFNQ TMKVEAENLA HKMSAKDQEL
SQKQNEIEKL QAVMQEEQLR FSELGASLRN LESLHSQSQE EQKVLTSELH SRIQMLRELE
MRNSKLEGDI SSKEENRNLS EINDTSISLE IQKNEISCLK KMKEKLEEEV AKQMNQSSAL
QVEIHCVKGN IDSMNRRYQK LIDQVSLTGF DPESLSYSVK KLQDENSKLV ELCTNQRDEN
NAVTGKLCEM DSILKRNADL EKLLLESNTK LDGSREKAKD LIERCESLRG EKSELAAERA
NLVSQLQIMT ANMQTLLEKN SVLEKSLSCA NIELESLRDK SKCFDDFFQF LKNDKSELMK
ERESLVSQLC KVEEKLGVLE KKYTELEVRY TDLQRDNKLK SHQVEELQVS LAAEKQESAN
YKRSTESRLA DLQKNVSFLR EECRSRKREY EDELDRVVNK QVEIFILQKL IEDLEQKNFS
LLIECQKHVE ASEFSEKLIA ELESENLEQQ MEAEIFLDEI DSLRGAIYQV IKALQVEADC
KTEQKITKDQ ISVSRALGEI DSLKGSLSSA EYEMHRLVVE NSVLLSLLGQ FQSDGLVLES
EKNILEKDLK TKIHQCGMLE KDKQDLQEAN RLLKSKLIKR EQQEQKLRAE LKFENLKFES
LHDSYMVLQQ DYSYTLNDNK TLLLKFSEFK DGMHVVEEEN DAILQEAVAL SNTCVVYRSF
GSEMAEEVED FVETVSSLRE ISTGLKRKVE TLEKKLEGKE KESQGLNKML ENLQEGLEED
NFLTGLLEHQ VSNVDEILEH REMEILEAEH MLKATNNENE ELHKEVEELR KDYEDSRRMR
ANLEWQISEL SDVAGRQEEE IRKLNALNEN LESEVQFLNK EIQRQQVREE YLSLELQEKS
NEIGLWDSAA TSFYFDLQVS AIRELILENK VNELSGVCEN LNDEVVTKTT KIKQMKETVG
FLESQVTELK SQLSAYDPVI ASLAGDVKAL EKSTHALTKF PATAYQQRVG NNLEESGSTT
SPCNGIVILK EINPSIKTIE QAFVKEKGRL SRQITRSTSQ KRRDRRKIEN IQPDDQVTGE
SRQPRLRPEM TEVKNELLMK DNPRDQVTDS LTYGRSQGTS HGSNDMFEFW DESAESETSV
NFLINSNKPQ RSLNSNLRHQ SRNPSIESDK AVGVVDKLEL SRNIEDKAKI LERLLSDSRR
LSSLRISLTD LKRKLEMNEK QRRFSNADLV IVKRQLKEME EAVSQLENTN EILSKEIEET
GDARDIYRKV VVEKSRSGSE KIEQLQNKMQ NIEQTVLKLE DGTKSKGRKM FSETRTVILL
RDIIHKGGKR SARKKKNRFC GCIRSSTKEE
