NET1C_ARATH
ID NET1C_ARATH Reviewed; 1111 AA.
AC Q9ZQX8;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Protein NETWORKED 1C {ECO:0000303|PubMed:22840520};
GN Name=NET1C {ECO:0000303|PubMed:22840520};
GN OrderedLocusNames=At4g02710 {ECO:0000312|Araport:AT4G02710};
GN ORFNames=T10P11.22 {ECO:0000312|EMBL:AAC78272.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=22840520; DOI=10.1016/j.cub.2012.06.041;
RA Deeks M.J., Calcutt J.R., Ingle E.K., Hawkins T.J., Chapman S.,
RA Richardson A.C., Mentlak D.A., Dixon M.R., Cartwright F., Smertenko A.P.,
RA Oparka K., Hussey P.J.;
RT "A superfamily of actin-binding proteins at the actin-membrane nexus of
RT higher plants.";
RL Curr. Biol. 22:1595-1600(2012).
RN [4]
RP GENE FAMILY.
RX PubMed=24926301; DOI=10.3389/fpls.2014.00254;
RA Hawkins T.J., Deeks M.J., Wang P., Hussey P.J.;
RT "The evolution of the actin binding NET superfamily.";
RL Front. Plant Sci. 5:254-254(2014).
CC -!- FUNCTION: Plant-specific actin binding protein. May be part of a
CC membrane-cytoskeletal adapter complex. {ECO:0000305|PubMed:22840520}.
CC -!- SIMILARITY: Belongs to the NET family. {ECO:0000305}.
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DR EMBL; AC002330; AAC78272.1; -; Genomic_DNA.
DR EMBL; AL161495; CAB77756.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82216.1; -; Genomic_DNA.
DR PIR; T01078; T01078.
DR RefSeq; NP_192180.1; NM_116505.2.
DR AlphaFoldDB; Q9ZQX8; -.
DR SMR; Q9ZQX8; -.
DR STRING; 3702.AT4G02710.1; -.
DR iPTMnet; Q9ZQX8; -.
DR PaxDb; Q9ZQX8; -.
DR PRIDE; Q9ZQX8; -.
DR ProteomicsDB; 251057; -.
DR EnsemblPlants; AT4G02710.1; AT4G02710.1; AT4G02710.
DR GeneID; 828199; -.
DR Gramene; AT4G02710.1; AT4G02710.1; AT4G02710.
DR KEGG; ath:AT4G02710; -.
DR Araport; AT4G02710; -.
DR TAIR; locus:2132348; AT4G02710.
DR eggNOG; ENOG502QQ6M; Eukaryota.
DR HOGENOM; CLU_001229_1_1_1; -.
DR InParanoid; Q9ZQX8; -.
DR OMA; SIRSEKH; -.
DR OrthoDB; 60151at2759; -.
DR PhylomeDB; Q9ZQX8; -.
DR PRO; PR:Q9ZQX8; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9ZQX8; baseline and differential.
DR Genevisible; Q9ZQX8; AT.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR InterPro; IPR011684; NAB.
DR Pfam; PF07765; KIP1; 1.
DR PROSITE; PS51774; NAB; 1.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1111
FT /note="Protein NETWORKED 1C"
FT /id="PRO_0000431851"
FT DOMAIN 13..93
FT /note="NAB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01110"
FT REGION 850..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 202..287
FT /evidence="ECO:0000255"
FT COILED 314..605
FT /evidence="ECO:0000255"
FT COILED 642..752
FT /evidence="ECO:0000255"
FT COILED 943..1009
FT /evidence="ECO:0000255"
SQ SEQUENCE 1111 AA; 127710 MW; 1DD5238EDE90F941 CRC64;
MEIAAKSNSK RMYSWWWDSH NTPKNSKWLQ DNLADMDSNV KQMIKVLEED ADSFARRAEM
YYRKRPELMK LVEEFYRAYR ALAERYNHAT GVIHKAHETI AEAFPNQVPL IFGDESHGGA
LTNDVDPQTP DMPPPFRARG NPDEFQQDAL GFSLSHVHDV KRNIDFSEEP LFVSNGKARK
GLNFNDHGDG KGRNGLKDHI LSESERASKA EAEVVALKDS LSKMQAEKQA SLALFEKNLE
RLSNLESEVS RAQADSRGIN DRAASAEAEI QTLRETLYKL ESEKESSFLQ YHKCLQKIAD
LEDGLSVAHK EAGERASKAE TETLALKRSL AKAETDKETA LIQYRQCLNT ISNLEERLRK
AEEDARLINE RAEKAGVEVE NLKQTVSKLI KDKEASELQF QQCLNIIASL KVKLHHAQEE
TQSLSHEIED GVAKLKFSEE KCLLLERSNQ NLHSELDSLL EKLGNQSQKL TEKQTELVKL
WSCVQAEHLH FQEAETAFQT LQQLHSQSQE ELNNLAVELQ TVSQIMKDME MRNNELHEEL
EQAKVENKGL NDLNFTMEKL VQKNLMLEKS ISYLNSELES FRRKLKTFEE ACQSLSEEKS
CLISENQHNV IENTVLIEWL RQLRLEAVGI ATEKTDLEGK AKTIGDKLTD AETENLQLKR
NLLSIRSEKH HLEDEITNVK DQLHEKEKEF EEIKMEKEKL IQEVFKERKQ VELWESQAAT
FFCDKQISVV HETLIEATTR ELAEACKNLE SKSASRDADI EKLKRSQTIV LLNESIKSLE
DYVFTHRESA GEVSKGADLM DEFLKLEGMC LRIKAIAEAI MEKEKFLMLE NTNTYSMLEA
SLKQIKELKT GGGRSMRKQD GGSGRMRKQS HETEMVMKDI VLDQTSDGSS YEIVSKKGNS
ELDHLGFVEL KPVKTHKTET KALSEESLIV EKVEIFDGFM DPNREVNKRR VLERLDSDLQ
KLENLQITVE DLKSKVETVE KEKTKVGENE YKTIKGQLEE GEEAIEKLFT VNRKLTTKAE
SEKDIDRRRR IFEHARRGTE KIGRLQSEIQ RIQFLLMKLE GEREHRLRSK ISDTKVLLRD
YIYGRTRSVS MKKRTKKRSV FCGCVQQPES P
