NET4B_ARATH
ID NET4B_ARATH Reviewed; 517 AA.
AC Q84VY2; O04345;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein NETWORKED 4B {ECO:0000303|PubMed:22840520};
GN Name=NET4B {ECO:0000303|PubMed:22840520};
GN OrderedLocusNames=At2g30500 {ECO:0000312|Araport:AT2G30500};
GN ORFNames=T6B20.15 {ECO:0000312|EMBL:AAB63087.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAO42872.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=22840520; DOI=10.1016/j.cub.2012.06.041;
RA Deeks M.J., Calcutt J.R., Ingle E.K., Hawkins T.J., Chapman S.,
RA Richardson A.C., Mentlak D.A., Dixon M.R., Cartwright F., Smertenko A.P.,
RA Oparka K., Hussey P.J.;
RT "A superfamily of actin-binding proteins at the actin-membrane nexus of
RT higher plants.";
RL Curr. Biol. 22:1595-1600(2012).
RN [6]
RP GENE FAMILY.
RX PubMed=24926301; DOI=10.3389/fpls.2014.00254;
RA Hawkins T.J., Deeks M.J., Wang P., Hussey P.J.;
RT "The evolution of the actin binding NET superfamily.";
RL Front. Plant Sci. 5:254-254(2014).
CC -!- FUNCTION: Plant-specific actin binding protein. May be part of a
CC membrane-cytoskeletal adapter complex. {ECO:0000305|PubMed:22840520}.
CC -!- SIMILARITY: Belongs to the NET family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB63087.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; U93215; AAB63087.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC08398.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08399.1; -; Genomic_DNA.
DR EMBL; BT004626; AAO42872.1; -; mRNA.
DR EMBL; AK227505; BAE99505.1; -; mRNA.
DR PIR; B84709; B84709.
DR RefSeq; NP_001189641.1; NM_001202712.2.
DR RefSeq; NP_001324131.1; NM_001336272.1.
DR RefSeq; NP_180608.2; NM_128602.5.
DR AlphaFoldDB; Q84VY2; -.
DR SMR; Q84VY2; -.
DR STRING; 3702.AT2G30500.2; -.
DR PaxDb; Q84VY2; -.
DR PRIDE; Q84VY2; -.
DR ProteomicsDB; 249045; -.
DR EnsemblPlants; AT2G30500.1; AT2G30500.1; AT2G30500.
DR EnsemblPlants; AT2G30500.2; AT2G30500.2; AT2G30500.
DR GeneID; 817600; -.
DR Gramene; AT2G30500.1; AT2G30500.1; AT2G30500.
DR Gramene; AT2G30500.2; AT2G30500.2; AT2G30500.
DR KEGG; ath:AT2G30500; -.
DR Araport; AT2G30500; -.
DR TAIR; locus:2064387; AT2G30500.
DR eggNOG; ENOG502QQTB; Eukaryota.
DR HOGENOM; CLU_032761_0_0_1; -.
DR InParanoid; Q84VY2; -.
DR OMA; QICLEER; -.
DR OrthoDB; 292839at2759; -.
DR PhylomeDB; Q84VY2; -.
DR PRO; PR:Q84VY2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q84VY2; baseline and differential.
DR Genevisible; Q84VY2; AT.
DR GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR InterPro; IPR011684; NAB.
DR Pfam; PF07765; KIP1; 1.
DR PROSITE; PS51774; NAB; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..517
FT /note="Protein NETWORKED 4B"
FT /id="PRO_0000431861"
FT DOMAIN 21..101
FT /note="NAB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01110"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 156..486
FT /evidence="ECO:0000255"
FT COMPBIAS 101..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..140
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 60234 MW; CB5E93EFD89D886B CRC64;
MASSTAQSKK QFKRSMTKKS HSWWWDSHNC PKNSKWLAEN LEKMDDRVNH MLKLIEEDAD
SFAKKAQMYF QKRPELIQLV EEFYRMYRAL AERYDQASGE LQKNHTSEIQ SQSSLEISSP
TKEKLSRRQS SHKEEEDSSS LTDSGSDSDH SSANDEDGDE ALIRRMAELE LELQETKQKL
LLQQESVDGD NNVDLLHKIT TYEGELKEAN EKMRMHEDEI ANLKNQLQSF MSFDTEDHLG
AEQKSVDLDK EDTKEDAVAT KVLALEEELS IAKEKLQHFE KETYSLKNEL EIGKAAEEKL
KSLQHELELA QRDADTYINK LNAEKKEVLK LQERLAMVKT SLQDRDNEIR ALKTAVSDAE
QKIFPEKAQI KGEMSKMLEE RSQLGEQLRE LESHIRLIKE EKAETEEKLR GGTEKISGMR
DESNVLREEI GKREEKIKET EKHMEELHME QVRLRRRSSE LTEEVERTRV SASEMAEQKR
EAIRQLCMSL DHYRDGYDRL WRVVAGHKSK RVVVLST
