ID   NEU1_STRCA              Reviewed;          93 AA.
AC   P15444;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Neurophysin 1;
OS   Struthio camelus (Common ostrich).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC   Struthio.
OX   NCBI_TaxID=8801;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=3436699; DOI=10.1111/j.1399-3011.1987.tb03374.x;
RA   Lazure C., Saayman H.S., Naude R.J., Oelofsen W., Chretien M.;
RT   "Complete amino acid sequence of a VLDV-type neurophysin from ostrich
RT   differs markedly from known mammalian neurophysins.";
RL   Int. J. Pept. Protein Res. 30:634-645(1987).
CC   -!- FUNCTION: Neurophysin 1 specifically binds oxytocin.
CC   -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR   PIR; JS0301; JS0301.
DR   AlphaFoldDB; P15444; -.
DR   SMR; P15444; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR   Gene3D; 2.60.9.10; -; 1.
DR   InterPro; IPR000981; Neurhyp_horm.
DR   InterPro; IPR036387; Neurhyp_horm_dom_sf.
DR   PANTHER; PTHR11681; PTHR11681; 1.
DR   Pfam; PF00184; Hormone_5; 1.
DR   PRINTS; PR00831; NEUROPHYSIN.
DR   SMART; SM00003; NH; 1.
DR   SUPFAM; SSF49606; SSF49606; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond.
FT   CHAIN           1..93
FT                   /note="Neurophysin 1"
FT                   /id="PRO_0000160935"
FT   DISULFID        10..54
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        13..27
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        21..44
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        28..34
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        61..74
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        68..86
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
FT   DISULFID        75..80
FT                   /evidence="ECO:0000250|UniProtKB:P01175"
SQ   SEQUENCE   93 AA;  9971 MW;  7CA8A9FBE2AC1444 CRC64;
     AVLDMDIRKC MPCGPRNKGH CFGPNICCGE ELGCYFGTSE TLRCQEENFL PTPCESGRKP
     CGNNEGSCAA SGICCSNEGC MVDSSCDQEV MFP