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NEUG_SERCA
ID   NEUG_SERCA              Reviewed;          73 AA.
AC   P54866;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Neurogranin;
DE            Short=NG;
DE   AltName: Full=Canarigranin;
GN   Name=NRGN; Synonyms=HAT14;
OS   Serinus canaria (Island canary) (Fringilla canaria).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Fringillidae;
OC   Carduelinae; Serinus.
OX   NCBI_TaxID=9135;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Wasserschlager;
RA   George J.M., Siepka S.M., Jin H., Holloway C.C., Clayton D.F.;
RL   Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a 'third messenger' substrate of protein kinase C-
CC       mediated molecular cascades during synaptic development and remodeling.
CC       Binds to calmodulin in the absence of calcium (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the neurogranin family. {ECO:0000305}.
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DR   EMBL; U56726; AAB01224.1; -; mRNA.
DR   RefSeq; XP_009096054.1; XM_009097806.2.
DR   AlphaFoldDB; P54866; -.
DR   SMR; P54866; -.
DR   Ensembl; ENSSCAT00000026778; ENSSCAP00000024069; ENSSCAG00000017228.
DR   GeneID; 103822794; -.
DR   KEGG; scan:103822794; -.
DR   CTD; 4900; -.
DR   GeneTree; ENSGT00440000039324; -.
DR   OMA; KSKDPEC; -.
DR   OrthoDB; 1639997at2759; -.
DR   Proteomes; UP000694409; Unassembled WGS sequence.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   Pfam; PF00612; IQ; 1.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Calmodulin-binding; Phosphoprotein; Reference proteome.
FT   CHAIN           1..73
FT                   /note="Neurogranin"
FT                   /id="PRO_0000159594"
FT   DOMAIN          26..55
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT   REGION          47..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..63
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         36
FT                   /note="Phosphoserine; by PKC"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   73 AA;  7853 MW;  01AD068CD461CC54 CRC64;
     MDCCNEGACT KLDEDILDIP LDDPDANAAA AKIQASFRGH MTRKKIKGGE IDRKTKDAEC
     ANSTRGGDLR NGD
 
 
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