ID   NEUH_CARCA              Reviewed;          36 AA.
AC   P11975;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Neuropeptide H;
DE   Contains:
DE     RecName: Full=Neuropeptide C;
DE   Contains:
DE     RecName: Full=Neuropeptide D;
DE   Contains:
DE     RecName: Full=Neuropeptide E;
DE   Contains:
DE     RecName: Full=Neuropeptide F;
DE   Contains:
DE     RecName: Full=Neuropeptide I;
OS   Cardisoma carnifex (Blue land crab).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;
OC   Eubrachyura; Grapsoidea; Gecarcinidae; Cardisoma.
OX   NCBI_TaxID=6766;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Sinus gland;
RX   PubMed=3298549; DOI=10.1111/j.1471-4159.1987.tb02902.x;
RA   Newcomb R.W.;
RT   "Amino acid sequences of neuropeptides in the sinus gland of the land crab
RT   Cardisoma carnifex: a novel neuropeptide proteolysis site.";
RL   J. Neurochem. 49:574-583(1987).
CC   -!- FUNCTION: Neuropeptide H is the precursor molecule for neuropeptides C,
CC       D, E, F and I, which arise by incomplete proteolysis of neuropeptide H.
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DR   PIR; A28503; A28503.
DR   AlphaFoldDB; P11975; -.
DR   SMR; P11975; -.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR005558; Crust_neurhormone_H.
DR   Pfam; PF03858; Crust_neuro_H; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hormone; Neuropeptide.
FT   PEPTIDE         1..36
FT                   /note="Neuropeptide H"
FT                   /id="PRO_0000021803"
FT   PEPTIDE         1..16
FT                   /note="Neuropeptide I"
FT                   /id="PRO_0000021804"
FT   PEPTIDE         1..10
FT                   /note="Neuropeptide C"
FT                   /id="PRO_0000021805"
FT   PEPTIDE         12..36
FT                   /note="Neuropeptide F"
FT                   /id="PRO_0000021806"
FT   PEPTIDE         12..16
FT                   /note="Neuropeptide E"
FT                   /id="PRO_0000021807"
FT   PEPTIDE         18..36
FT                   /note="Neuropeptide D"
FT                   /id="PRO_0000021808"
FT   REGION          17..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   36 AA;  3643 MW;  16D9C69865679DCE CRC64;
     RSADGFGRME SLLTSLRGSA ESPAALGEAS AAHPLE