ID   NEUV_SCLRE              Reviewed;          27 AA.
AC   P42992;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Vasotocin-neurophysin VT;
DE            Short=VT;
DE   Contains:
DE     RecName: Full=Hydrin-2;
DE     AltName: Full=Hydrin II;
DE   Contains:
DE     RecName: Full=Vasotocin;
DE   Contains:
DE     RecName: Full=Neurophysin VT;
DE   Flags: Fragment;
OS   Sclerophrys regularis (Common African toad) (Bufo regularis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Sclerophrys.
OX   NCBI_TaxID=1978144;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT GLY-9.
RX   PubMed=8097151; DOI=10.1016/0300-9629(93)90454-c;
RA   Chauvet J., Ouedraogo Y., Michel G., Acher R.;
RT   "Vasotocin and hydrin 2 (vasotocinyl-Gly) in the African toad Bufo
RT   regularis: study under various environmental conditions.";
RL   Comp. Biochem. Physiol. 104A:497-502(1993).
CC   -!- FUNCTION: Vasotocin is an antidiuretic hormone.
CC   -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR   PIR; A49155; A49155.
DR   AlphaFoldDB; P42992; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR   InterPro; IPR000981; Neurhyp_horm.
DR   InterPro; IPR022423; Neurohypophysial_hormone_CS.
DR   Pfam; PF00220; Hormone_4; 1.
DR   PRINTS; PR00831; NEUROPHYSIN.
DR   PROSITE; PS00264; NEUROHYPOPHYS_HORM; 1.
PE   1: Evidence at protein level;
KW   Amidation; Cleavage on pair of basic residues; Direct protein sequencing;
KW   Disulfide bond; Hormone.
FT   PEPTIDE         1..10
FT                   /note="Hydrin-2"
FT                   /id="PRO_0000020538"
FT   PEPTIDE         1..9
FT                   /note="Vasotocin"
FT                   /id="PRO_0000020539"
FT   CHAIN           13..>27
FT                   /note="Neurophysin VT"
FT                   /id="PRO_0000020540"
FT   MOD_RES         9
FT                   /note="Glycine amide"
FT                   /evidence="ECO:0000269|PubMed:8097151"
FT   DISULFID        1..6
FT   UNSURE          11..12
FT   NON_TER         27
SQ   SEQUENCE   27 AA;  2924 MW;  D4C68FEEE4FF5079 CRC64;
     CYIQNCPRGG KRSYPDTAVP QCIPCGP