ID   NFIP1_XENLA             Reviewed;         212 AA.
AC   Q6GLN5;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=NEDD4 family-interacting protein 1;
GN   Name=ndfip1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in Golgi structure maintenance.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
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DR   EMBL; BC074425; AAH74425.1; -; mRNA.
DR   RefSeq; NP_001086285.1; NM_001092816.1.
DR   RefSeq; XP_018106481.1; XM_018250992.1.
DR   AlphaFoldDB; Q6GLN5; -.
DR   DNASU; 444714; -.
DR   GeneID; 444714; -.
DR   KEGG; xla:444714; -.
DR   CTD; 444714; -.
DR   Xenbase; XB-GENE-961963; ndfip1.L.
DR   OrthoDB; 1495850at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 444714; Expressed in brain and 19 other tissues.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR   GO; GO:0007034; P:vacuolar transport; IEA:InterPro.
DR   InterPro; IPR019325; NEDD4/Bsd2.
DR   PANTHER; PTHR13396; PTHR13396; 1.
DR   Pfam; PF10176; DUF2370; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..212
FT                   /note="NEDD4 family-interacting protein 1"
FT                   /id="PRO_0000076273"
FT   TOPO_DOM        1..107
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        129..134
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        156..163
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        185..212
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           30..33
FT                   /note="PPxY motif 1"
FT   MOTIF           55..58
FT                   /note="PPxY motif 2"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   212 AA;  24087 MW;  96EC2B4AA6A94E3E CRC64;
     MSEQSSSSRY QQLQNEEEPG ENAQASADAP PPYSSIAGES SGLFDYKDEL GFPKPPSYNV
     ATTLPSYDEA ERSKAEATIP LVPGRDDDFV ARDDFDDADQ LRIGNDGIFM LTFFMAFLFN
     WIGFFLSFCL TSSAAGRYGA ISGFGLSLIK WILIVRFSTY FPGYFDGQYW LWWVFLVLGF
     LLFLRGFINY AKVRKMPDNF STLPRTRVLF IY