ID   NFRB_ECO57              Reviewed;         745 AA.
AC   P0AFA6; P31599;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Bacteriophage N4 adsorption protein B;
GN   Name=nfrB; OrderedLocusNames=Z0699, ECs0601;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Required for bacteriophage N4 adsorption. May be a component
CC       of the phage receptor (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
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DR   EMBL; AE005174; AAG54896.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34024.1; -; Genomic_DNA.
DR   PIR; A90704; A90704.
DR   PIR; D85554; D85554.
DR   RefSeq; NP_308628.1; NC_002695.1.
DR   RefSeq; WP_000383932.1; NZ_SDVX01000001.1.
DR   AlphaFoldDB; P0AFA6; -.
DR   SMR; P0AFA6; -.
DR   STRING; 155864.EDL933_0625; -.
DR   EnsemblBacteria; AAG54896; AAG54896; Z0699.
DR   EnsemblBacteria; BAB34024; BAB34024; ECs_0601.
DR   GeneID; 916959; -.
DR   KEGG; ece:Z0699; -.
DR   KEGG; ecs:ECs_0601; -.
DR   PATRIC; fig|386585.9.peg.708; -.
DR   eggNOG; COG1215; Bacteria.
DR   HOGENOM; CLU_019733_1_0_6; -.
DR   OMA; KTMHDFP; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.300.160; -; 1.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR037257; T2SS_E_N_sf.
DR   InterPro; IPR007831; T2SS_GspE_N.
DR   Pfam; PF13632; Glyco_trans_2_3; 1.
DR   Pfam; PF05157; T2SSE_N; 1.
DR   SUPFAM; SSF160246; SSF160246; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..745
FT                   /note="Bacteriophage N4 adsorption protein B"
FT                   /id="PRO_0000096797"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   745 AA;  85319 MW;  B596A5D5B64654C0 CRC64;
     MDWLLDVFAT WLYGLKVIAI TLAVIMFISG LDDFFIDVVY WVRRIKRKLS VYRRYPRMSY
     RELYKPDEKP LAIMVPAWNE TGVIGNMAEL AATTLDYENY HIFVGTYPND PDTQRDVDEV
     CARFPNVHKV VCARPGPTSK ADCLNNVLDA ITQFERSANF AFAGFILHDA EDVISPMELR
     LFNYLVERKD LIQIPVYPFE REWTHFTSMT YIDEFSELHG KDVPVREALA GQVPSAGVGT
     CFSRRAVTAL LADGDGIAFD VQSLTEDYDI GFRLKEKGMT EIFVRFPVVD EAKEREQRKF
     LQHARTSNMI CVREYFPDTF STAVRQKSRW IIGIVFQGFK THKWTSSLTL NYFLWRDRKG
     AISNFVSFLA MLVMIQLLLL LAYESLWPDA WHFLSIFSGS AWLMTLLWLN FGLMVNRIVQ
     RVIFVTGYYG LTQGLLSVLR LFWGNLINFM ANWRALKQVL QHGDPRRVAW DKTTHDFPSV
     TGDTRSLRPL GQILLENQVI TEEQLDTALR NRVEGLRLGG SMLMQGLISA EQLAQALAEQ
     NGVAWESIDA WQIPSSLIAE MPASVALHYA VLPLRLENDE LIVGSEDGID PVSLAALTRK
     VGRKVRYVIV LRGQIVTGLR HWYARRRGHD PRAMLYNAVQ HQWLTEQQAG EIWRQYVPHQ
     FLFAEILTTL GHINRSAINV LLLRHERSSL PLGKFLVTEG VISQETLDRV LTIQRELQVS
     MQSLLLKAGL NTEQVAQLES ENEGE