NFYA9_ARATH
ID NFYA9_ARATH Reviewed; 303 AA.
AC Q945M9; Q9LIH3;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Nuclear transcription factor Y subunit A-9;
DE Short=AtNF-YA-9;
GN Name=NFYA9; OrderedLocusNames=At3g20910; ORFNames=MFD22.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
CC -!- FUNCTION: Stimulates the transcription of various genes by recognizing
CC and binding to a CCAAT motif in promoters. {ECO:0000250}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q945M9; Q9SMP0: NFYC1; NbExp=3; IntAct=EBI-15191941, EBI-2125944;
CC Q945M9; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-15191941, EBI-2466050;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in inflorescence, stems, flowers and
CC siliques. {ECO:0000269|PubMed:11867211}.
CC -!- SIMILARITY: Belongs to the NFYA/HAP2 subunit family.
CC {ECO:0000255|PROSITE-ProRule:PRU00966}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB01900.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP001304; BAB01900.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76439.1; -; Genomic_DNA.
DR EMBL; AF412056; AAL06509.1; -; mRNA.
DR EMBL; AY093971; AAM16232.1; -; mRNA.
DR EMBL; AY087696; AAM65233.1; -; mRNA.
DR RefSeq; NP_566670.1; NM_112983.5.
DR AlphaFoldDB; Q945M9; -.
DR SMR; Q945M9; -.
DR BioGRID; 6972; 22.
DR IntAct; Q945M9; 19.
DR STRING; 3702.AT3G20910.1; -.
DR iPTMnet; Q945M9; -.
DR PaxDb; Q945M9; -.
DR PRIDE; Q945M9; -.
DR ProteomicsDB; 250529; -.
DR EnsemblPlants; AT3G20910.1; AT3G20910.1; AT3G20910.
DR GeneID; 821640; -.
DR Gramene; AT3G20910.1; AT3G20910.1; AT3G20910.
DR KEGG; ath:AT3G20910; -.
DR Araport; AT3G20910; -.
DR TAIR; locus:2088791; AT3G20910.
DR eggNOG; KOG1561; Eukaryota.
DR HOGENOM; CLU_064594_1_0_1; -.
DR InParanoid; Q945M9; -.
DR OMA; ENQNNWE; -.
DR OrthoDB; 931258at2759; -.
DR PhylomeDB; Q945M9; -.
DR PRO; PR:Q945M9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q945M9; baseline and differential.
DR Genevisible; Q945M9; AT.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0055046; P:microgametogenesis; IMP:TAIR.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0009555; P:pollen development; IMP:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR GO; GO:0010262; P:somatic embryogenesis; IMP:TAIR.
DR InterPro; IPR018362; CCAAT-binding_factor_CS.
DR InterPro; IPR001289; NFYA.
DR PANTHER; PTHR12632; PTHR12632; 2.
DR Pfam; PF02045; CBFB_NFYA; 1.
DR PRINTS; PR00616; CCAATSUBUNTB.
DR SMART; SM00521; CBF; 1.
DR PROSITE; PS00686; NFYA_HAP2_1; 1.
DR PROSITE; PS51152; NFYA_HAP2_2; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..303
FT /note="Nuclear transcription factor Y subunit A-9"
FT /id="PRO_0000198779"
FT DNA_BIND 199..224
FT /note="NFYA/HAP2-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00966"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 44..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 169..192
FT /note="Subunit association domain (SAD)"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..219
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 303 AA; 33151 MW; 6F26FD9B263C36B3 CRC64;
MGIEDMHSKS DSGGNKVDSE VHGTVSSSIN SLNPWHRAAA ACNANSSVEA GDKSSKSIAL
ALESNGSKSP SNRDNTVNKE SQVTTSPQSA GDYSDKNQES LHHGITQPPP HPQLVGHTVG
WASSNPYQDP YYAGVMGAYG HHPLGFVPYG GMPHSRMPLP PEMAQEPVFV NAKQYQAILR
RRQARAKAEL EKKLIKSRKP YLHESRHQHA MRRPRGTGGR FAKKTNTEAS KRKAEEKSNG
HVTQSPSSSN SDQGEAWNGD YRTPQGDEMQ SSAYKRREEG ECSGQQWNSL SSNHPSQARL
AIK
