NFYB7_ARATH
ID NFYB7_ARATH Reviewed; 215 AA.
AC Q9SIT9; Q1PF75;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Nuclear transcription factor Y subunit B-7 {ECO:0000303|PubMed:11250072};
DE Short=AtNF-YB-7 {ECO:0000303|PubMed:11250072};
DE Short=AtNF-YB7 {ECO:0000303|PubMed:25490919};
GN Name=NFYB7 {ECO:0000303|PubMed:11250072};
GN OrderedLocusNames=At2g13570 {ECO:0000312|Araport:AT2G13570};
GN ORFNames=T10F5.11 {ECO:0000312|EMBL:AAD22680.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=11250072; DOI=10.1016/s0378-1119(01)00323-7;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of the CCAAT-binding NF-Y subunits in Arabidopsis thaliana.";
RL Gene 264:173-185(2001).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
RN [7]
RP INTERACTION WITH DPB3-1, AND REPRESSION BY HEAT STRESS AND DEHYDRATION.
RC STRAIN=cv. Columbia;
RX PubMed=25490919; DOI=10.1105/tpc.114.132928;
RA Sato H., Mizoi J., Tanaka H., Maruyama K., Qin F., Osakabe Y., Morimoto K.,
RA Ohori T., Kusakabe K., Nagata M., Shinozaki K., Yamaguchi-Shinozaki K.;
RT "Arabidopsis DPB3-1, a DREB2A interactor, specifically enhances heat
RT stress-induced gene expression by forming a heat stress-specific
RT transcriptional complex with NF-Y subunits.";
RL Plant Cell 26:4954-4973(2014).
RN [8]
RP REVIEW.
RX PubMed=28119722; DOI=10.3389/fpls.2016.02045;
RA Zhao H., Wu D., Kong F., Lin K., Zhang H., Li G.;
RT "The Arabidopsis thaliana Nuclear Factor Y Transcription Factors.";
RL Front. Plant Sci. 7:2045-2045(2016).
CC -!- FUNCTION: Component of the NF-Y/HAP transcription factor complex (By
CC similarity). The NF-Y complex stimulates the transcription of various
CC genes by recognizing and binding to a CCAAT motif in promoters (By
CC similarity). {ECO:0000250|UniProtKB:Q84W66}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC (By similarity). NF-YB and NF-YC
CC must interact and dimerize for NF-YA association and DNA binding (By
CC similarity). Binds directly with DPB3-1 (PubMed:25490919).
CC {ECO:0000250|UniProtKB:P23511, ECO:0000269|PubMed:25490919}.
CC -!- INTERACTION:
CC Q9SIT9; Q8LAT0: ATHB-20; NbExp=3; IntAct=EBI-4459822, EBI-4465764;
CC Q9SIT9; Q9LN09: NF-YC10; NbExp=3; IntAct=EBI-4459822, EBI-4461992;
CC Q9SIT9; Q9LHG0: NF-YC11; NbExp=4; IntAct=EBI-4459822, EBI-4452389;
CC Q9SIT9; Q9SMP0: NFYC1; NbExp=3; IntAct=EBI-4459822, EBI-2125944;
CC Q9SIT9; Q58CM8: NFYC10; NbExp=3; IntAct=EBI-4459822, EBI-15191737;
CC Q9SIT9; Q9FGP8: NFYC7; NbExp=3; IntAct=EBI-4459822, EBI-2466133;
CC Q9SIT9; Q4PSE2: NFYC8; NbExp=3; IntAct=EBI-4459822, EBI-15191571;
CC Q9SIT9; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-4459822, EBI-2466050;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers and green siliques.
CC {ECO:0000269|PubMed:11250072}.
CC -!- INDUCTION: Repressed by heat and dehydration stress.
CC {ECO:0000269|PubMed:25490919}.
CC -!- SIMILARITY: Belongs to the NFYB/HAP3 subunit family. {ECO:0000305}.
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DR EMBL; AC007063; AAD22680.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06243.1; -; Genomic_DNA.
DR EMBL; DQ446491; ABE65807.1; -; mRNA.
DR EMBL; BT025276; ABF19029.1; -; mRNA.
DR PIR; F84508; F84508.
DR RefSeq; NP_178981.1; NM_126937.2.
DR AlphaFoldDB; Q9SIT9; -.
DR SMR; Q9SIT9; -.
DR BioGRID; 1204; 62.
DR IntAct; Q9SIT9; 56.
DR STRING; 3702.AT2G13570.1; -.
DR PaxDb; Q9SIT9; -.
DR PRIDE; Q9SIT9; -.
DR ProteomicsDB; 250530; -.
DR EnsemblPlants; AT2G13570.1; AT2G13570.1; AT2G13570.
DR GeneID; 815843; -.
DR Gramene; AT2G13570.1; AT2G13570.1; AT2G13570.
DR KEGG; ath:AT2G13570; -.
DR Araport; AT2G13570; -.
DR TAIR; locus:2054095; AT2G13570.
DR eggNOG; KOG0869; Eukaryota.
DR HOGENOM; CLU_066247_2_1_1; -.
DR InParanoid; Q9SIT9; -.
DR OMA; NIDSIHW; -.
DR OrthoDB; 1529111at2759; -.
DR PhylomeDB; Q9SIT9; -.
DR PRO; PR:Q9SIT9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIT9; baseline and differential.
DR Genevisible; Q9SIT9; AT.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IBA:GO_Central.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IEP:UniProtKB.
DR GO; GO:0009414; P:response to water deprivation; IEP:UniProtKB.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR027113; Transc_fact_NFYB/HAP3.
DR InterPro; IPR003956; Transcrpt_fac_NFYB/HAP3_CS.
DR PANTHER; PTHR11064; PTHR11064; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
DR PROSITE; PS00685; NFYB_HAP3; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..215
FT /note="Nuclear transcription factor Y subunit B-7"
FT /id="PRO_0000204621"
FT DNA_BIND 41..47
FT /evidence="ECO:0000250|UniProtKB:P13434"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..79
FT /note="Subunit association domain (SAD)"
FT /evidence="ECO:0000250"
FT REGION 130..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 215 AA; 24619 MW; 0615B2B7A097DD25 CRC64;
MTEESPEEDH GSPGVAETNP GSPSSKTNNN NNNNKEQDRF LPIANVGRIM KKVLPGNGKI
SKDAKETVQE CVSEFISFVT GEASDKCQRE KRKTINGDDI IWAITTLGFE DYVAPLKVYL
CKYRDTEGEK VNSPKQQQQR QQQQQIQQQN HHNYQFQEQD QNNNNMSCTS YISHHHPSPF
LPVDHQPFPN IAFSPKSLQK QFPQQHDNNI DSIHW
