NFYBA_ARATH
ID NFYBA_ARATH Reviewed; 176 AA.
AC Q67XJ2; Q9LFI3;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Nuclear transcription factor Y subunit B-10;
DE Short=AtNF-YB-10;
GN Name=NFYB10; OrderedLocusNames=At3g53340; ORFNames=F4P12_40;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
CC -!- FUNCTION: Component of the NF-Y/HAP transcription factor complex. The
CC NF-Y complex stimulates the transcription of various genes by
CC recognizing and binding to a CCAAT motif in promoters.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q67XJ2; Q58CM8: NFYC10; NbExp=3; IntAct=EBI-2475824, EBI-15191737;
CC Q67XJ2; Q9FGP8: NFYC7; NbExp=3; IntAct=EBI-2475824, EBI-2466133;
CC Q67XJ2; Q4PSE2: NFYC8; NbExp=3; IntAct=EBI-2475824, EBI-15191571;
CC Q67XJ2; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-2475824, EBI-2466050;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in the whole plant, except roots.
CC {ECO:0000269|PubMed:11867211}.
CC -!- SIMILARITY: Belongs to the NFYB/HAP3 subunit family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB67641.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL132966; CAB67641.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE79070.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65605.1; -; Genomic_DNA.
DR EMBL; AK176827; BAD44590.1; -; mRNA.
DR PIR; T45874; T45874.
DR RefSeq; NP_001327562.1; NM_001339611.1.
DR RefSeq; NP_190902.2; NM_115194.3.
DR AlphaFoldDB; Q67XJ2; -.
DR SMR; Q67XJ2; -.
DR BioGRID; 9819; 22.
DR IntAct; Q67XJ2; 18.
DR STRING; 3702.AT3G53340.1; -.
DR PaxDb; Q67XJ2; -.
DR PRIDE; Q67XJ2; -.
DR ProteomicsDB; 251058; -.
DR EnsemblPlants; AT3G53340.1; AT3G53340.1; AT3G53340.
DR EnsemblPlants; AT3G53340.5; AT3G53340.5; AT3G53340.
DR GeneID; 824502; -.
DR Gramene; AT3G53340.1; AT3G53340.1; AT3G53340.
DR Gramene; AT3G53340.5; AT3G53340.5; AT3G53340.
DR KEGG; ath:AT3G53340; -.
DR Araport; AT3G53340; -.
DR TAIR; locus:2083941; AT3G53340.
DR eggNOG; KOG0869; Eukaryota.
DR HOGENOM; CLU_066247_13_1_1; -.
DR InParanoid; Q67XJ2; -.
DR OrthoDB; 1529111at2759; -.
DR PhylomeDB; Q67XJ2; -.
DR PRO; PR:Q67XJ2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q67XJ2; baseline and differential.
DR Genevisible; Q67XJ2; AT.
DR GO; GO:0016602; C:CCAAT-binding factor complex; IBA:GO_Central.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0019760; P:glucosinolate metabolic process; IMP:TAIR.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR027113; Transc_fact_NFYB/HAP3.
DR InterPro; IPR003956; Transcrpt_fac_NFYB/HAP3_CS.
DR PANTHER; PTHR11064; PTHR11064; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
DR PROSITE; PS00685; NFYB_HAP3; 1.
PE 1: Evidence at protein level;
KW Acetylation; Activator; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q9SLG0"
FT CHAIN 2..176
FT /note="Nuclear transcription factor Y subunit B-10"
FT /id="PRO_0000204624"
FT DNA_BIND 34..40
FT /evidence="ECO:0000250"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..72
FT /note="Subunit association domain (SAD)"
FT /evidence="ECO:0000250"
FT REGION 121..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:Q9SLG0"
SQ SEQUENCE 176 AA; 19155 MW; 7F26A068342ED485 CRC64;
MAESQTGGGG GGSHESGGDQ SPRSLNVREQ DRFLPIANIS RIMKRGLPLN GKIAKDAKET
MQECVSEFIS FVTSEASDKC QREKRKTING DDLLWAMATL GFEDYIDPLK VYLMRYREME
GDTKGSGKGG ESSAKRDGQP SQVSQFSQVP QQGSFSQGPY GNSQGSNMMV QMPGTE
