ID   NFYB_XENLA              Reviewed;         122 AA.
AC   P25211;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Nuclear transcription factor Y subunit beta;
DE   AltName: Full=CAAT box DNA-binding protein subunit B;
DE   AltName: Full=Nuclear transcription factor Y subunit B;
DE            Short=NF-YB;
DE   Flags: Fragment;
GN   Name=nfyb;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1549471; DOI=10.1093/nar/20.5.1087;
RA   Li X.-Y., Mantovani R., Hooft van Huijsduijnen R., Andre I., Benoist C.,
RA   Mathis D.;
RT   "Evolutionary variation of the CCAAT-binding transcription factor NF-Y.";
RL   Nucleic Acids Res. 20:1087-1091(1992).
CC   -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC       transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC       box motif found in the promoters of its target genes. NF-Y can function
CC       as both an activator and a repressor, depending on its interacting
CC       cofactors.
CC   -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC       components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC       dimerize for NF-YA association and DNA binding (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DOMAIN: Can be divided into 3 domains: the weakly conserved A domain,
CC       the highly conserved B domain thought to be involved in subunit
CC       interaction and DNA binding, and the Glu-rich C domain.
CC   -!- SIMILARITY: Belongs to the NFYB/HAP3 subunit family. {ECO:0000305}.
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DR   EMBL; X59709; CAA42229.1; -; mRNA.
DR   PIR; S22819; S22819.
DR   AlphaFoldDB; P25211; -.
DR   SMR; P25211; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0016602; C:CCAAT-binding factor complex; IEA:InterPro.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR003958; CBFA_NFYB_domain.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR027113; Transc_fact_NFYB/HAP3.
DR   InterPro; IPR003956; Transcrpt_fac_NFYB/HAP3_CS.
DR   PANTHER; PTHR11064; PTHR11064; 1.
DR   Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
DR   PROSITE; PS00685; NFYB_HAP3; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           <1..122
FT                   /note="Nuclear transcription factor Y subunit beta"
FT                   /id="PRO_0000204614"
FT   REGION          <1..57
FT                   /note="B domain"
FT   REGION          <1..12
FT                   /note="Subunit association domain (SAD)"
FT                   /evidence="ECO:0000250"
FT   REGION          58..122
FT                   /note="C domain"
FT   NON_TER         1
SQ   SEQUENCE   122 AA;  13498 MW;  E76AD9FBC638F53A CRC64;
     VQECVSEFIS FITSEASERC HQEKRKTING EDILFAMSTL GFDSYVEPLK LYLQKFREAM
     KGEKGIGGTV TTGDGLGEDL AEEPFTSQIP AGLITTDGQQ QNVMVYTTSY QQISGVQQIQ
     FS