NFYC3_ARATH
ID NFYC3_ARATH Reviewed; 217 AA.
AC Q9ZVL3;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 138.
DE RecName: Full=Nuclear transcription factor Y subunit C-3;
DE Short=AtNF-YC-3;
GN Name=NFYC3; OrderedLocusNames=At1g54830; ORFNames=F14C21.41, T22H22.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=11250072; DOI=10.1016/s0378-1119(01)00323-7;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of the CCAAT-binding NF-Y subunits in Arabidopsis thaliana.";
RL Gene 264:173-185(2001).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
CC -!- FUNCTION: Stimulates the transcription of various genes by recognizing
CC and binding to a CCAAT motif in promoters. {ECO:0000250}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q9ZVL3; Q84MC7: PYL9; NbExp=3; IntAct=EBI-2125961, EBI-2349513;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:11250072}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family. {ECO:0000305}.
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DR EMBL; AC005388; AAC64892.1; -; Genomic_DNA.
DR EMBL; AC069144; AAG51114.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33151.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33152.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33153.1; -; Genomic_DNA.
DR EMBL; AY062775; AAL32853.1; -; mRNA.
DR EMBL; AY087517; AAM65059.1; -; mRNA.
DR EMBL; AY081654; AAM10216.1; -; mRNA.
DR RefSeq; NP_175880.1; NM_104356.3.
DR RefSeq; NP_849808.1; NM_179477.2.
DR RefSeq; NP_974030.1; NM_202301.2.
DR PDB; 5G49; X-ray; 2.30 A; B=55-148.
DR PDB; 6R0M; X-ray; 2.30 A; B/D=55-148.
DR PDB; 6R0N; X-ray; 2.10 A; B=55-148.
DR PDB; 6R2V; X-ray; 2.50 A; C=55-148.
DR PDB; 7CVQ; X-ray; 3.30 A; A/F/K/P=55-148.
DR PDBsum; 5G49; -.
DR PDBsum; 6R0M; -.
DR PDBsum; 6R0N; -.
DR PDBsum; 6R2V; -.
DR PDBsum; 7CVQ; -.
DR AlphaFoldDB; Q9ZVL3; -.
DR SMR; Q9ZVL3; -.
DR BioGRID; 27147; 24.
DR IntAct; Q9ZVL3; 3.
DR STRING; 3702.AT1G54830.3; -.
DR PaxDb; Q9ZVL3; -.
DR EnsemblPlants; AT1G54830.1; AT1G54830.1; AT1G54830.
DR EnsemblPlants; AT1G54830.2; AT1G54830.2; AT1G54830.
DR EnsemblPlants; AT1G54830.3; AT1G54830.3; AT1G54830.
DR GeneID; 841922; -.
DR Gramene; AT1G54830.1; AT1G54830.1; AT1G54830.
DR Gramene; AT1G54830.2; AT1G54830.2; AT1G54830.
DR Gramene; AT1G54830.3; AT1G54830.3; AT1G54830.
DR KEGG; ath:AT1G54830; -.
DR Araport; AT1G54830; -.
DR TAIR; locus:2010980; AT1G54830.
DR eggNOG; KOG1657; Eukaryota.
DR HOGENOM; CLU_045277_0_0_1; -.
DR InParanoid; Q9ZVL3; -.
DR OMA; FWETQFK; -.
DR OrthoDB; 1558176at2759; -.
DR PhylomeDB; Q9ZVL3; -.
DR PRO; PR:Q9ZVL3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZVL3; baseline and differential.
DR Genevisible; Q9ZVL3; AT.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0003712; F:transcription coregulator activity; IDA:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IGI:TAIR.
DR GO; GO:0009740; P:gibberellic acid mediated signaling pathway; IGI:TAIR.
DR GO; GO:0048574; P:long-day photoperiodism, flowering; IMP:TAIR.
DR GO; GO:2000306; P:positive regulation of photomorphogenesis; IMP:TAIR.
DR GO; GO:0010029; P:regulation of seed germination; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Activator; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..217
FT /note="Nuclear transcription factor Y subunit C-3"
FT /id="PRO_0000218252"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 66..68
FT /evidence="ECO:0007829|PDB:5G49"
FT HELIX 73..81
FT /evidence="ECO:0007829|PDB:6R0N"
FT STRAND 83..85
FT /evidence="ECO:0007829|PDB:6R2V"
FT HELIX 92..118
FT /evidence="ECO:0007829|PDB:6R0N"
FT STRAND 122..124
FT /evidence="ECO:0007829|PDB:6R0N"
FT HELIX 126..135
FT /evidence="ECO:0007829|PDB:6R0N"
FT HELIX 137..142
FT /evidence="ECO:0007829|PDB:6R0N"
FT TURN 143..145
FT /evidence="ECO:0007829|PDB:6R0N"
SQ SEQUENCE 217 AA; 24312 MW; C0623D936B3C20A7 CRC64;
MDQQGQSSAM NYGSNPYQTN AMTTTPTGSD HPAYHQIHQQ QQQQLTQQLQ SFWETQFKEI
EKTTDFKNHS LPLARIKKIM KADEDVRMIS AEAPVVFARA CEMFILELTL RSWNHTEENK
RRTLQKNDIA AAVTRTDIFD FLVDIVPRED LRDEVLGGVG AEAATAAGYP YGYLPPGTAP
IGNPGMVMGN PGAYPPNPYM GQPMWQQPGP EQQDPDN
