NFYC5_ARATH
ID NFYC5_ARATH Reviewed; 186 AA.
AC Q9FGP6;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Nuclear transcription factor Y subunit C-5;
DE Short=AtNF-YC-5;
GN Name=NFYC5; OrderedLocusNames=At5g50490; ORFNames=MBA10.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=11250072; DOI=10.1016/s0378-1119(01)00323-7;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of the CCAAT-binding NF-Y subunits in Arabidopsis thaliana.";
RL Gene 264:173-185(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
CC -!- FUNCTION: Stimulates the transcription of various genes by recognizing
CC and binding to a CCAAT motif in promoters. {ECO:0000250}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in inflorescences and flowers.
CC {ECO:0000269|PubMed:11250072}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family. {ECO:0000305}.
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DR EMBL; AB025619; BAB09134.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95951.1; -; Genomic_DNA.
DR EMBL; BX833977; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_199860.1; NM_124431.3.
DR AlphaFoldDB; Q9FGP6; -.
DR SMR; Q9FGP6; -.
DR BioGRID; 20363; 10.
DR IntAct; Q9FGP6; 2.
DR STRING; 3702.AT5G50490.1; -.
DR PaxDb; Q9FGP6; -.
DR PRIDE; Q9FGP6; -.
DR EnsemblPlants; AT5G50490.1; AT5G50490.1; AT5G50490.
DR GeneID; 835117; -.
DR Gramene; AT5G50490.1; AT5G50490.1; AT5G50490.
DR KEGG; ath:AT5G50490; -.
DR Araport; AT5G50490; -.
DR TAIR; locus:2159722; AT5G50490.
DR eggNOG; KOG1657; Eukaryota.
DR HOGENOM; CLU_045277_0_2_1; -.
DR InParanoid; Q9FGP6; -.
DR OMA; HEFPITR; -.
DR OrthoDB; 1622159at2759; -.
DR PhylomeDB; Q9FGP6; -.
DR PRO; PR:Q9FGP6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGP6; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..186
FT /note="Nuclear transcription factor Y subunit C-5"
FT /id="PRO_0000218254"
FT REGION 166..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 14
FT /note="D -> E (in Ref. 3; BX833977)"
FT /evidence="ECO:0000305"
FT CONFLICT 55
FT /note="I -> M (in Ref. 3; BX833977)"
FT /evidence="ECO:0000305"
FT CONFLICT 84
FT /note="E -> K (in Ref. 3; BX833977)"
FT /evidence="ECO:0000305"
FT CONFLICT 160
FT /note="I -> K (in Ref. 3; BX833977)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 186 AA; 20400 MW; 13E755923B10822D CRC64;
MENNNNNHQQ PPKDNEQLKS FWSKGMEGDL NVKNHEFPIS RIKRIMKFDP DVSMIAAEAP
NLLSKACEMF VMDLTMRSWL HAQESNRLTI RKSDVDAVVS QTVIFDFLRD DVPKDEGEPV
VAAADPVDDV ADHVAVPDLN NEELPPGTVI GTPVCYGLGI HAPHPQMPGA WTEEDATGAN
GGNGGN
