NFYC8_ARATH
ID NFYC8_ARATH Reviewed; 187 AA.
AC Q4PSE2;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Nuclear transcription factor Y subunit C-8;
DE Short=AtNF-YC-8;
GN Name=NFYC8; OrderedLocusNames=At5g27910; ORFNames=F14I23.70, F15F15.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=11250072; DOI=10.1016/s0378-1119(01)00323-7;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of the CCAAT-binding NF-Y subunits in Arabidopsis thaliana.";
RL Gene 264:173-185(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11867211; DOI=10.1016/s0378-1119(01)00833-2;
RA Gusmaroli G., Tonelli C., Mantovani R.;
RT "Regulation of novel members of the Arabidopsis thaliana CCAAT-binding
RT nuclear factor Y subunits.";
RL Gene 283:41-48(2002).
CC -!- FUNCTION: Stimulates the transcription of various genes by recognizing
CC and binding to a CCAAT motif in promoters. {ECO:0000250}.
CC -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC dimerize for NF-YA association and DNA binding (By similarity).
CC {ECO:0000250}.
CC -!- INTERACTION:
CC Q4PSE2; Q9LU68: CIA2; NbExp=3; IntAct=EBI-15191571, EBI-4435051;
CC Q4PSE2; O23379: COL11; NbExp=3; IntAct=EBI-15191571, EBI-15191913;
CC Q4PSE2; Q9LJ44: COL12; NbExp=4; IntAct=EBI-15191571, EBI-15192317;
CC Q4PSE2; O82256: COL13; NbExp=3; IntAct=EBI-15191571, EBI-15191569;
CC Q4PSE2; O22800-2: COL14; NbExp=3; IntAct=EBI-15191571, EBI-15192033;
CC Q4PSE2; Q9C7E8: COL15; NbExp=3; IntAct=EBI-15191571, EBI-2465998;
CC Q4PSE2; Q8RWD0: COL16; NbExp=3; IntAct=EBI-15191571, EBI-15192471;
CC Q4PSE2; Q96502: COL2; NbExp=3; IntAct=EBI-15191571, EBI-4425260;
CC Q4PSE2; Q9M9B3: COL8; NbExp=3; IntAct=EBI-15191571, EBI-15192397;
CC Q4PSE2; P94077: LSD1; NbExp=4; IntAct=EBI-15191571, EBI-5849461;
CC Q4PSE2; Q5Q0A4: MYC6.9; NbExp=3; IntAct=EBI-15191571, EBI-15191663;
CC Q4PSE2; Q9SLG0: NFYB1; NbExp=3; IntAct=EBI-15191571, EBI-2126009;
CC Q4PSE2; Q67XJ2: NFYB10; NbExp=3; IntAct=EBI-15191571, EBI-2475824;
CC Q4PSE2; Q9FGJ3: NFYB2; NbExp=5; IntAct=EBI-15191571, EBI-15192505;
CC Q4PSE2; O23310: NFYB3; NbExp=3; IntAct=EBI-15191571, EBI-4452064;
CC Q4PSE2; O04027: NFYB4; NbExp=3; IntAct=EBI-15191571, EBI-1751677;
CC Q4PSE2; O82248: NFYB5; NbExp=3; IntAct=EBI-15191571, EBI-2475759;
CC Q4PSE2; Q84W66-2: NFYB6; NbExp=3; IntAct=EBI-15191571, EBI-15191739;
CC Q4PSE2; Q9SIT9: NFYB7; NbExp=3; IntAct=EBI-15191571, EBI-4459822;
CC Q4PSE2; Q8VYK4: NFYB8; NbExp=3; IntAct=EBI-15191571, EBI-15192579;
CC Q4PSE2; O82277: TCP10; NbExp=3; IntAct=EBI-15191571, EBI-3133327;
CC Q4PSE2; Q9S7W5: TCP13; NbExp=3; IntAct=EBI-15191571, EBI-4424877;
CC Q4PSE2; Q93Z00: TCP14; NbExp=3; IntAct=EBI-15191571, EBI-4424563;
CC Q4PSE2; Q9C9L2: TCP15; NbExp=4; IntAct=EBI-15191571, EBI-4426144;
CC Q4PSE2; Q9FMX2: TCP7; NbExp=3; IntAct=EBI-15191571, EBI-15192677;
CC Q4PSE2; O64722: ZHD3; NbExp=3; IntAct=EBI-15191571, EBI-1806244;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers and siliques.
CC {ECO:0000269|PubMed:11250072}.
CC -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family. {ECO:0000305}.
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DR EMBL; AC007399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC007627; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93743.1; -; Genomic_DNA.
DR EMBL; DQ056694; AAY78840.1; -; mRNA.
DR RefSeq; NP_198143.1; NM_122673.2.
DR AlphaFoldDB; Q4PSE2; -.
DR SMR; Q4PSE2; -.
DR BioGRID; 18131; 73.
DR IntAct; Q4PSE2; 69.
DR STRING; 3702.AT5G27910.1; -.
DR PaxDb; Q4PSE2; -.
DR PRIDE; Q4PSE2; -.
DR EnsemblPlants; AT5G27910.1; AT5G27910.1; AT5G27910.
DR GeneID; 832857; -.
DR Gramene; AT5G27910.1; AT5G27910.1; AT5G27910.
DR KEGG; ath:AT5G27910; -.
DR Araport; AT5G27910; -.
DR TAIR; locus:2143315; AT5G27910.
DR eggNOG; KOG1657; Eukaryota.
DR HOGENOM; CLU_045277_0_2_1; -.
DR InParanoid; Q4PSE2; -.
DR OMA; IGTPVCC; -.
DR OrthoDB; 1558176at2759; -.
DR PhylomeDB; Q4PSE2; -.
DR PRO; PR:Q4PSE2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q4PSE2; baseline and differential.
DR Genevisible; Q4PSE2; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..187
FT /note="Nuclear transcription factor Y subunit C-8"
FT /id="PRO_0000218257"
FT REGION 163..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..187
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 187 AA; 20609 MW; 453BEC4758AC4F34 CRC64;
MENNNGNNQL PPKGNEQLKS FWSKEMEGNL DFKNHDLPIT RIKKIMKYDP DVTMIASEAP
ILLSKACEMF IMDLTMRSWL HAQESKRVTL QKSNVDAAVA QTVIFDFLLD DDIEVKRESV
AAAADPVAMP PIDDGELPPG MVIGTPVCCS LGIHQPQPQM QAWPGAWTSV SGEEEEARGK
KGGDDGN
