ID   NFYC_PONAB              Reviewed;         335 AA.
AC   Q5RA23;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Nuclear transcription factor Y subunit gamma;
DE   AltName: Full=CAAT box DNA-binding protein subunit C;
DE   AltName: Full=Nuclear transcription factor Y subunit C;
DE            Short=NF-YC;
GN   Name=NFYC;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC       transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC       box motif found in the promoters of its target genes. NF-Y can function
CC       as both an activator and a repressor, depending on its interacting
CC       cofactors.
CC   -!- SUBUNIT: Heterotrimeric transcription factor composed of three
CC       components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and
CC       dimerize for NF-YA association and DNA binding (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NFYC/HAP5 subunit family. {ECO:0000305}.
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DR   EMBL; CR859200; CAH91387.1; -; mRNA.
DR   RefSeq; NP_001125820.1; NM_001132348.1.
DR   RefSeq; XP_009249997.1; XM_009251722.1.
DR   AlphaFoldDB; Q5RA23; -.
DR   SMR; Q5RA23; -.
DR   STRING; 9601.ENSPPYP00000001715; -.
DR   GeneID; 100172748; -.
DR   KEGG; pon:100172748; -.
DR   CTD; 4802; -.
DR   eggNOG; KOG1657; Eukaryota.
DR   HOGENOM; CLU_045277_2_1_1; -.
DR   InParanoid; Q5RA23; -.
DR   OrthoDB; 1558176at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR007125; Histone_H2A/H2B/H3.
DR   Pfam; PF00125; Histone; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..335
FT                   /note="Nuclear transcription factor Y subunit gamma"
FT                   /id="PRO_0000218248"
SQ   SEQUENCE   335 AA;  37150 MW;  3081F6D5ACC602BA CRC64;
     MSTEGGFGGT SSSDAQQSLQ SFWPRVMEEI RNLTVKDFRV QELPLARIKK IMKLDEDVKM
     ISAEAPVLFA KAAQIFITEL TLRAWIHTED NKRRTLQRND IAMAITKFDQ FDFLIDIVPR
     DELKPPKRQE DVRQSVTPAE PVQYYFTLAQ QPAAVQVQGQ QQGQQTTSST TTIQPGQIII
     AQPQQGQTTP VTMQVGEGQQ VQIVQAQPQG QAQQAQSGTG QTMQVMQQII TNTGEIQQIP
     VQLNAGQLQY IRLAQPVSGT QVVQGQIQTL ATNAQQITQT EVQQGQQQFS QFTDGQQLYQ
     IQQVTMPAGQ DLAQPMFIQS ANQPSDGQAP QVTGD