NGA2_ARATH
ID NGA2_ARATH Reviewed; 299 AA.
AC Q9M268; Q8GYG4; Q8LEW1;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=B3 domain-containing transcription factor NGA2;
DE AltName: Full=Protein NGATHA 2;
GN Name=NGA2; OrderedLocusNames=At3g61970; ORFNames=F21F14.140;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION.
RX PubMed=16603651; DOI=10.1105/tpc.105.040725;
RA Alvarez J.P., Pekker I., Goldshmidt A., Blum E., Amsellem Z., Eshed Y.;
RT "Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and
RT localized regulation of multiple targets in diverse species.";
RL Plant Cell 18:1134-1151(2006).
RN [7]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- FUNCTION: Regulates lateral organ growth. Functionally redundant with
CC NGA1, NGA3 and NGA4. {ECO:0000269|PubMed:16603651}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM67302.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AL138642; CAB71904.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE80288.1; -; Genomic_DNA.
DR EMBL; AK117646; BAC42301.1; -; mRNA.
DR EMBL; BT025866; ABF85768.1; -; mRNA.
DR EMBL; AY085197; AAM67302.1; ALT_INIT; mRNA.
DR PIR; T47989; T47989.
DR RefSeq; NP_191756.1; NM_116062.3.
DR AlphaFoldDB; Q9M268; -.
DR SMR; Q9M268; -.
DR BioGRID; 10684; 4.
DR IntAct; Q9M268; 3.
DR STRING; 3702.AT3G61970.1; -.
DR PaxDb; Q9M268; -.
DR PRIDE; Q9M268; -.
DR ProteomicsDB; 251112; -.
DR EnsemblPlants; AT3G61970.1; AT3G61970.1; AT3G61970.
DR GeneID; 825370; -.
DR Gramene; AT3G61970.1; AT3G61970.1; AT3G61970.
DR KEGG; ath:AT3G61970; -.
DR Araport; AT3G61970; -.
DR TAIR; locus:2079537; AT3G61970.
DR eggNOG; ENOG502QSHQ; Eukaryota.
DR HOGENOM; CLU_038898_3_2_1; -.
DR InParanoid; Q9M268; -.
DR OMA; DKLYIDW; -.
DR OrthoDB; 661086at2759; -.
DR PhylomeDB; Q9M268; -.
DR PRO; PR:Q9M268; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M268; baseline and differential.
DR Genevisible; Q9M268; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009908; P:flower development; IMP:TAIR.
DR GO; GO:0048366; P:leaf development; IMP:TAIR.
DR GO; GO:1901371; P:regulation of leaf morphogenesis; IGI:TAIR.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR044800; LEC2-like.
DR PANTHER; PTHR31140; PTHR31140; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR PROSITE; PS50863; B3; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..299
FT /note="B3 domain-containing transcription factor NGA2"
FT /id="PRO_0000375092"
FT DNA_BIND 23..129
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 197
FT /note="M -> I (in Ref. 5; AAM67302)"
FT /evidence="ECO:0000305"
FT CONFLICT 245
FT /note="I -> M (in Ref. 5; AAM67302)"
FT /evidence="ECO:0000305"
FT CONFLICT 269
FT /note="E -> K (in Ref. 3; BAC42301)"
FT /evidence="ECO:0000305"
FT CONFLICT 291
FT /note="P -> S (in Ref. 5; AAM67302)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 299 AA; 34270 MW; 2AB841F179DD174B CRC64;
MNQEDKEKPI EEASSSMERE HMFDKVVTPS DVGKLNRLVI PKQHAERYFP LDNSTTNDSN
KGLLLNFEDR SGNSWRFRYS YWNSSQSYVM TKGWSRFVKD KKLDAGDIVS FQRDSCNKDK
LYIDWRRRPK IPDHHHQQFA GAMFPRFYTF PHPQMPTNYE THNLYHRFHQ RDLGIGYYVR
SMERSHPTAV IESVPVMMQR RAQVASMASR GEKRLRLFGV DMECGGGGGS VNSTEEESSS
SGGSIPRGRV SMVGAGSLLQ LRLVSSDDES LVAMEAASLE DHHFFTKKGK PSLSFDLDR
