NGA3_ARATH
ID NGA3_ARATH Reviewed; 358 AA.
AC Q9MAN1;
DT 26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=B3 domain-containing transcription factor NGA3;
DE AltName: Full=Protein NGATHA3;
GN Name=NGA3; OrderedLocusNames=At1g01030; ORFNames=T25K16.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP FUNCTION.
RX PubMed=16603651; DOI=10.1105/tpc.105.040725;
RA Alvarez J.P., Pekker I., Goldshmidt A., Blum E., Amsellem Z., Eshed Y.;
RT "Endogenous and synthetic microRNAs stimulate simultaneous, efficient, and
RT localized regulation of multiple targets in diverse species.";
RL Plant Cell 18:1134-1151(2006).
RN [5]
RP GENE FAMILY.
RX PubMed=18986826; DOI=10.1016/j.tplants.2008.09.006;
RA Swaminathan K., Peterson K., Jack T.;
RT "The plant B3 superfamily.";
RL Trends Plant Sci. 13:647-655(2008).
CC -!- FUNCTION: Regulates lateral organ growth. Functionally redundant with
CC NGA1, NGA2 and NGA4. {ECO:0000269|PubMed:16603651}.
CC -!- INTERACTION:
CC Q9MAN1; A0A1I9LTW1: At3g54390; NbExp=3; IntAct=EBI-15216492, EBI-15191983;
CC Q9MAN1; Q8H174: IAA31; NbExp=3; IntAct=EBI-15216492, EBI-3946408;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00326}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BX814729; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC007323; AAF26476.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27219.1; -; Genomic_DNA.
DR EMBL; BX814729; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; B86141; B86141.
DR RefSeq; NP_171611.1; NM_099985.3.
DR AlphaFoldDB; Q9MAN1; -.
DR SMR; Q9MAN1; -.
DR BioGRID; 24556; 4.
DR IntAct; Q9MAN1; 3.
DR STRING; 3702.AT1G01030.1; -.
DR PaxDb; Q9MAN1; -.
DR PRIDE; Q9MAN1; -.
DR ProteomicsDB; 249119; -.
DR EnsemblPlants; AT1G01030.1; AT1G01030.1; AT1G01030.
DR GeneID; 839321; -.
DR Gramene; AT1G01030.1; AT1G01030.1; AT1G01030.
DR KEGG; ath:AT1G01030; -.
DR Araport; AT1G01030; -.
DR TAIR; locus:2200950; AT1G01030.
DR eggNOG; ENOG502QSHQ; Eukaryota.
DR HOGENOM; CLU_038898_3_2_1; -.
DR InParanoid; Q9MAN1; -.
DR OMA; NDYDQHE; -.
DR OrthoDB; 661086at2759; -.
DR PhylomeDB; Q9MAN1; -.
DR PRO; PR:Q9MAN1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9MAN1; baseline and differential.
DR Genevisible; Q9MAN1; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009908; P:flower development; IMP:TAIR.
DR GO; GO:0048366; P:leaf development; IMP:TAIR.
DR GO; GO:1901371; P:regulation of leaf morphogenesis; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd10017; B3_DNA; 1.
DR Gene3D; 2.40.330.10; -; 1.
DR InterPro; IPR003340; B3_DNA-bd.
DR InterPro; IPR015300; DNA-bd_pseudobarrel_sf.
DR InterPro; IPR044800; LEC2-like.
DR PANTHER; PTHR31140; PTHR31140; 1.
DR Pfam; PF02362; B3; 1.
DR SMART; SM01019; B3; 1.
DR SUPFAM; SSF101936; SSF101936; 1.
DR PROSITE; PS50863; B3; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..358
FT /note="B3 domain-containing transcription factor NGA3"
FT /id="PRO_0000375093"
FT DNA_BIND 56..162
FT /note="TF-B3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00326"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 310..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 358 AA; 40288 MW; DCF366CC2D388DAC CRC64;
MDLSLAPTTT TSSDQEQDRD QELTSNIGAS SSSGPSGNNN NLPMMMIPPP EKEHMFDKVV
TPSDVGKLNR LVIPKQHAER YFPLDSSNNQ NGTLLNFQDR NGKMWRFRYS YWNSSQSYVM
TKGWSRFVKE KKLDAGDIVS FQRGIGDESE RSKLYIDWRH RPDMSLVQAH QFGNFGFNFN
FPTTSQYSNR FHPLPEYNSV PIHRGLNIGN HQRSYYNTQR QEFVGYGYGN LAGRCYYTGS
PLDHRNIVGS EPLVIDSVPV VPGRLTPVML PPLPPPPSTA GKRLRLFGVN MECGNDYNQQ
EESWLVPRGE IGASSSSSSA LRLNLSTDHD DDNDDGDDGD DDQFAKKGKS SLSLNFNP
