NH150_CAEEL
ID NH150_CAEEL Reviewed; 342 AA.
AC O17573;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Nuclear hormone receptor family member nhr-150;
GN Name=nhr-150; ORFNames=C06B8.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z81463; CAB03850.1; -; Genomic_DNA.
DR PIR; T18993; T18993.
DR RefSeq; NP_506854.1; NM_074453.1.
DR AlphaFoldDB; O17573; -.
DR SMR; O17573; -.
DR STRING; 6239.C06B8.1; -.
DR PaxDb; O17573; -.
DR EnsemblMetazoa; C06B8.1.1; C06B8.1.1; WBGene00007367.
DR GeneID; 182297; -.
DR KEGG; cel:CELE_C06B8.1; -.
DR UCSC; C06B8.1; c. elegans.
DR CTD; 182297; -.
DR WormBase; C06B8.1; CE07969; WBGene00007367; nhr-150.
DR eggNOG; KOG3575; Eukaryota.
DR GeneTree; ENSGT00390000009496; -.
DR HOGENOM; CLU_007368_1_0_1; -.
DR InParanoid; O17573; -.
DR PhylomeDB; O17573; -.
DR PRO; PR:O17573; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00007367; Expressed in embryo and 2 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR042936; Nhr-150.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46800; PTHR46800; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..342
FT /note="Nuclear hormone receptor family member nhr-150"
FT /id="PRO_0000223596"
FT DOMAIN 94..341
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 1..71
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 2..22
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 39..54
FT /note="NR C4-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 342 AA; 39284 MW; 325E587528CCAF13 CRC64;
MCQVCGAAEA DLHFGGISCR ACAAFFRRFF LSKKQSKKCT CKTRILDSHP CRSCRILKCF
EAGMTSKKIQ SGRDKTSTKA ISCISTESTS NSLSARIIPR SSLNIHGAVH LWQEFENTRA
CKKGTKRNAL IVSTSSAGDM DSTWKMVINL FSSLGELEIK DKTALLRNFM PKFIQIDSVP
YFAANIDVFK NIGRDEYESS IIDFYDGVLP ETNTISKKDT IRIFEPYWNF YTNKVILPIA
LMKLEGPEFM ALVWLLFFDN GYTNLSDKCR EACRNIKKVI LRELRSYQID RNFDRNRFFE
ILEALQLVER GEKKFMEEMV ICELLNIKID PGFMEIIRES KL
