ID   NH153_CAEEL             Reviewed;         415 AA.
AC   O01929;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 146.
DE   RecName: Full=Nuclear hormone receptor family member nhr-153;
GN   Name=nhr-153; ORFNames=C13C4.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Orphan nuclear receptor.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC       {ECO:0000305}.
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DR   EMBL; Z92825; CAB07313.1; -; Genomic_DNA.
DR   PIR; T19234; T19234.
DR   RefSeq; NP_506038.1; NM_073637.1.
DR   AlphaFoldDB; O01929; -.
DR   SMR; O01929; -.
DR   PaxDb; O01929; -.
DR   PRIDE; O01929; -.
DR   EnsemblMetazoa; C13C4.1.1; C13C4.1.1; WBGene00007546.
DR   UCSC; C13C4.1; c. elegans.
DR   WormBase; C13C4.1; CE52953; WBGene00007546; nhr-153.
DR   eggNOG; ENOG502TG66; Eukaryota.
DR   HOGENOM; CLU_007368_3_1_1; -.
DR   InParanoid; O01929; -.
DR   OMA; NQCPSVC; -.
DR   OrthoDB; 1669484at2759; -.
DR   PhylomeDB; O01929; -.
DR   PRO; PR:O01929; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00007546; Expressed in material anatomical entity and 4 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004879; F:nuclear receptor activity; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048856; P:anatomical structure development; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0042594; P:response to starvation; IEP:WormBase.
DR   GO; GO:0007614; P:short-term memory; IGI:WormBase.
DR   Gene3D; 1.10.565.10; -; 1.
DR   Gene3D; 3.30.50.10; -; 1.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF48508; SSF48508; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..415
FT                   /note="Nuclear hormone receptor family member nhr-153"
FT                   /id="PRO_0000223597"
FT   DOMAIN          170..406
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT   DNA_BIND        26..105
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT   ZN_FING         29..49
FT                   /note="NR C4-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT   ZN_FING         65..88
FT                   /note="NR C4-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ   SEQUENCE   415 AA;  47568 MW;  C8297E0F789BE6D9 CRC64;
     MTPPQKSKPK RNRRKIYKIL PQNQCPSVCQ ICRNPAIGYH YEVPSCNGCK TFFRRTIITG
     RKFKCFKVSN CLDGNDVIDT SKRVCRACRF EKCVQAGMNP MAIQAEAKTD EGEELKKLIA
     KKFENGEKLN DGTVFFNVHD RLNQILGKLI KIETKLEKVH DNGMPMGFLD QRDLSTALSS
     KVIYNNMEIP SMSYTPVKIS KNTGLPKRRS RNFVHSSCLA SIEYSKTFDF SSAIDISSKI
     ILLKNTALSC ANLTNAYTTF RKLKSDTLLY PDGSIYGPPR RKNGPLIEKQ RSFLQNTLIS
     FMTNNVDKTE YILLKAIVLC NPAIIDLPYA DSKHIQRERE VYAQCLFRYC LLQHGTLHGP
     ARFSALLSIF NVLENQQKEQ KDYYLYIKLI HSQKHKDPEV LKKKCISVIY DQIMD