NH164_CAEEL
ID NH164_CAEEL Reviewed; 389 AA.
AC O17657;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Nuclear hormone receptor family member nhr-164;
GN Name=nhr-164; ORFNames=C41G6.5;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; Z81047; CAB02829.1; -; Genomic_DNA.
DR PIR; T19883; T19883.
DR RefSeq; NP_001309454.1; NM_001322592.1.
DR AlphaFoldDB; O17657; -.
DR SMR; O17657; -.
DR STRING; 6239.C41G6.5; -.
DR PaxDb; O17657; -.
DR EnsemblMetazoa; C41G6.5.1; C41G6.5.1; WBGene00008056.
DR GeneID; 183381; -.
DR KEGG; cel:CELE_C41G6.5; -.
DR UCSC; C41G6.5; c. elegans.
DR CTD; 183381; -.
DR WormBase; C41G6.5; CE51345; WBGene00008056; nhr-164.
DR eggNOG; KOG3575; Eukaryota.
DR GeneTree; ENSGT00970000195849; -.
DR HOGENOM; CLU_066719_0_0_1; -.
DR InParanoid; O17657; -.
DR OrthoDB; 1214776at2759; -.
DR PhylomeDB; O17657; -.
DR PRO; PR:O17657; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00105; zf-C4; 1.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..389
FT /note="Nuclear hormone receptor family member nhr-164"
FT /id="PRO_0000223599"
FT DOMAIN 157..388
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 39..113
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 42..63
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 79..95
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 389 AA; 45184 MW; 20445C217941447A CRC64;
MDYGRTRRKR LLMNGSDESE NQYAQHYVEF LETMSYTKFG VCAVCGFSCQ VQYHFGGVVC
GACSAFFRRT VSLNIRYLCD GDNQCKSMLK KCRACRFESC VKTAGMKRSL VRRKKPTIKT
TPLYIKNRET HVRNEDVLRA FIPSYTHPSP ANETVEDKGK FSEKLKLSHG NILKFYINQV
RYAKRKNTNI FTIKTTEDFM RLVNFQRKIA DETCSSFPGV ELIDENNILI LRKYLQFSSV
WIESTWTYWI TNSSVSVDNM EMDKRLKELI EHVKSTLLIS LSQLKLNIFE FAAFKSFFVW
KLVFHKTSVA MKTIGQEHYE CVSSALKSYY QTYTSMDSTE IAVRIGEITL LLSLVFVSKI
DLKSKSSELN FQQIYHDMAK LYVHLGLPF
