NH167_CAEEL
ID NH167_CAEEL Reviewed; 343 AA.
AC O17683;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Nuclear hormone receptor family member nhr-167;
GN Name=nhr-167; ORFNames=C49F5.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; Z81485; CAB03978.1; -; Genomic_DNA.
DR PIR; T20073; T20073.
DR RefSeq; NP_510004.1; NM_077603.3.
DR AlphaFoldDB; O17683; -.
DR SMR; O17683; -.
DR PaxDb; O17683; -.
DR EnsemblMetazoa; C49F5.4.1; C49F5.4.1; WBGene00008208.
DR GeneID; 183613; -.
DR KEGG; cel:CELE_C49F5.4; -.
DR UCSC; C49F5.4; c. elegans.
DR CTD; 183613; -.
DR WormBase; C49F5.4; CE08855; WBGene00008208; nhr-167.
DR eggNOG; ENOG502THC0; Eukaryota.
DR GeneTree; ENSGT00970000195839; -.
DR HOGENOM; CLU_007368_3_0_1; -.
DR InParanoid; O17683; -.
DR OMA; CHVIGKH; -.
DR OrthoDB; 1364888at2759; -.
DR PhylomeDB; O17683; -.
DR PRO; PR:O17683; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00008208; Expressed in larva and 1 other tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..343
FT /note="Nuclear hormone receptor family member nhr-167"
FT /id="PRO_0000223600"
FT DOMAIN 101..339
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 5..81
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 8..28
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 45..64
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 343 AA; 40069 MW; 042D16970616E657 CRC64;
MNALHQKCAV CGRFTTEFNY SVLSCNSCKI FFRRLIVRTV PIKKCFRGER CFEKTPYIFK
CTSCRFQKCL YVGMTLPSYL LVLEQNKEQR LAITIDCVRN THNKRMDSLF NFFVTEMNPN
VDDIVELNKI TYTKRDEHIR MDFQTWAFHS CVTTIDFMKQ FPFVNLLRST DQMILLKESY
VKLGALISAT RAYSSKKQCI SFPDGTDCLP KTQWTVPKIS PNLENRIRCR VIDKLRELNI
QNDEFYLLSV LLFCNPAITN LSENGQLLLT SYQKMYSSAL LYYCLLTYQK SGPSRFSELL
GLFTLLGQHY DDIIHYYVLM QLNQSEVELK KLVKDGIEAA YKS