NH197_CAEEL
ID NH197_CAEEL Reviewed; 340 AA.
AC O17931;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 2.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Nuclear hormone receptor family member nhr-197;
GN Name=nhr-197; ORFNames=K06B4.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; Z83233; CAB05764.2; -; Genomic_DNA.
DR PIR; T23368; T23368.
DR RefSeq; NP_506901.1; NM_074500.1.
DR AlphaFoldDB; O17931; -.
DR SMR; O17931; -.
DR PaxDb; O17931; -.
DR EnsemblMetazoa; K06B4.7.1; K06B4.7.1; WBGene00010602.
DR GeneID; 187055; -.
DR KEGG; cel:CELE_K06B4.7; -.
DR UCSC; K06B4.7; c. elegans.
DR CTD; 187055; -.
DR WormBase; K06B4.7; CE25931; WBGene00010602; nhr-197.
DR GeneTree; ENSGT00970000195839; -.
DR HOGENOM; CLU_007368_3_0_1; -.
DR InParanoid; O17931; -.
DR OrthoDB; 1873688at2759; -.
DR PhylomeDB; O17931; -.
DR PRO; PR:O17931; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..340
FT /note="Nuclear hormone receptor family member nhr-197"
FT /id="PRO_0000223603"
FT DOMAIN 98..337
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 1..75
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 3..23
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 39..58
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 340 AA; 39079 MW; 9421ABAF1E759784 CRC64;
MNCVVCSGRA TNRNYGAMSC FACKMFFHRT VYKNLLFRCK RIQNCTIHFK IFPKCRACRF
QKCLIVGMTL APLNDGIVSI GNQSDYSYAK LLDDLKFKND KNYSHFVNFY SLEDPSLADI
LKDRGIMKLV KRTPKTLNDV DQWSIMMAYS RISYFLDFNF IRDLDSSDKN TLFKYNISRA
GCLALAKCAF NENKPKLTFP NDVDAFPSEM YNLCGSSTAV LNQVSGQVIA KFVELKIKDE
EYLLLILVMF CNPSISNDFS DKTKLALSSH QQAFCSALFR YCQINYSKSA PTRFTELLSL
FGIVNKSVDN MNNLSMMLQF CEPKFQFKRI MQDLFSNSLL
