NH213_CAEEL
ID NH213_CAEEL Reviewed; 414 AA.
AC O18048;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 156.
DE RecName: Full=Nuclear hormone receptor family member nhr-213;
GN Name=nhr-213; ORFNames=T06C12.13;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; Z81116; CAB03309.1; -; Genomic_DNA.
DR PIR; T24574; T24574.
DR RefSeq; NP_506974.1; NM_074573.1.
DR AlphaFoldDB; O18048; -.
DR BioGRID; 52844; 1.
DR DIP; DIP-24574N; -.
DR STRING; 6239.T06C12.13a; -.
DR PaxDb; O18048; -.
DR PRIDE; O18048; -.
DR EnsemblMetazoa; T06C12.13a.1; T06C12.13a.1; WBGene00011520.
DR GeneID; 188172; -.
DR UCSC; T06C12.13; c. elegans.
DR CTD; 188172; -.
DR WormBase; T06C12.13a; CE16363; WBGene00011520; nhr-213.
DR eggNOG; KOG3575; Eukaryota.
DR GeneTree; ENSGT00970000196028; -.
DR InParanoid; O18048; -.
DR OMA; ELHEHYT; -.
DR OrthoDB; 1136195at2759; -.
DR PhylomeDB; O18048; -.
DR PRO; PR:O18048; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00011520; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR ExpressionAtlas; O18048; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..414
FT /note="Nuclear hormone receptor family member nhr-213"
FT /id="PRO_0000223605"
FT DOMAIN 162..414
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 21..99
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 24..44
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 62..82
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 414 AA; 48018 MW; 0C715B3C7D24B4BA CRC64;
MSSTPSTSDT SSESSTSPAT IVLCKVCALS AHGSHFGVLA CRACAAFFRR TVVLERQKQY
KCKKGKNECP VDTAERYQCR LCRYNKCVDL GMTPENVQFN RESASRTRKR KNENSIAQTN
SFKLIPRSDN AFLGKPRTIM DISSLSTKIK SVLNGKTYNL DSAAKKMNSL EAAEYALKKW
RSQQKTEDKM EKVGELPVRQ LFVIFEKQMV MIAEWLIHNP DFRMLDEEEK YLYFKAVWNM
WRRFERFEMS VKMFGNQVLT KRKFAISNEK LMVMDSCIDY SEITDLPNSK VAEMFRLTRS
KLFHQLAKPL MELNPSSIEM AYMLTQLSWQ IAGKKMQGNV IEIGERVCDN LADDLHSYYQ
KNEKRSNYAG RLVRLMNIVN AMKKIHLQRK NTMELARIFE MFKVDFSDPD IFDC
